Jiménez-López J, Márquez-Acosta G, Olaya GEJ, Gómez-Pue D, Arteaga GAC

Language: Spanish
References: 55
Page: 106-112
PDF size: 458.98 Kb.

ABSTRACT

Phyllodes tumors is a rare fibroepithelial neoplasm; constitute about 0.3-0.9% of breast tumors and 2-3% of fibroepithelial breast tumors. They usually occur in middle-aged to elderly women but can occur at any age. No single feature is reliable to predict clinical behavior of phyllodes tumors. Several histological parameters should be evaluated, including stromal cellularity, atypia, mitoses, stromal overgrowth, infiltrative borders, and presence or absence of necrosis. Most of these tumors are benign, but up to 30% show malignant stroma. Metastases usually are hematogenous rather than lymphatic have been reported to occur at a rate of 13% as malignant phyllodes tumors usually spread by a hematogenous rather than a lymphatic route; axillary lymph node dissection is generally not recommended. The benign and malignant tumors phyllodes resort locally in 25% and follow up of patients is recomended.

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