medigraphic.com

2011, Number 1

<< Back Next >>

Rev Hosp Jua Mex 2011; 78 (1)

Deterioro en el pronóstico del trasplante corneal por glaucoma perioperatorio

Ríos GLC, Razo-Blanco HDM, Flores HGL, Lima GV

Language: Spanish
References: 23
Page: 18-23
PDF size: 35.43 Kb.


ABSTRACT

Introduction. Glaucoma worsens the prognosis of a penetrating keratoplasty, but the proportion of eyes with a corneal graft that are affected by perioperative glaucoma in our population has not been reported. Objetive. To identify the frequency of perioperative glaucoma in penetrating keratoplasty by prognostic groups, and compare the proportions of eyes whose prognosis would change when the disease existed between prognosis groups. Material and methods. We included patients with penetrating keratoplasties performed between 2003 and 2008; we evaluated the IOP before and after in postoperative days 1, 7, 30, 90, and 180. The proportions of preoperative and postoperative glaucoma were identified and compared between each prognostic group and the rest using χ2. A p value ‹ 0.05 was considered a statistical difference. Results. A hundred and two eyes of patients aged 14- 89 years were evaluated; 13 had preoperative glaucoma (12.7%); 9 out of 89 eyes without preoperative glaucoma developed postoperative glaucoma (10.1%). Perioperative glaucoma would worsen graft prognosis in 22 eyes (21.6%, 95% confidence intervals 13.6 to 29.6). Glaucoma was associated statistically with prognostic group 2 preoperatively, but not postoperatively nor globally. Conclusions. Perioperative glaucoma could worsen the prognosis in up to 29.6% of corneal grafts. Control of preoperative intraocular hypertension and early detection of postoperative intraocular hypertension must be treatment priorities, in order to achieve the best result after a penetrating keratoplasty.


REFERENCES

  1. Hawa-Montiel H. Trasplante de córnea. Criterio médico-quirúrgico. Rev Invest Clin 2005; 57: 358-67.

  2. Cursiefen C, Chen L, Dana MR, Streilein JW. Corneal lymphangiogenesis: evidence, mechanisms and implications for corneal transplant immunology. Cornea 2003; 22: 273-81.

  3. Dorrepaal SJ, Cao KY, Slomovic AR. Indications for penetrating keratoplasty in a tertiary referral centre in Canada, 1996-2004. Can J Ophthalmol 2007; 42: 244-50.

  4. Benson WE. Penetrating keratoplasty and keratoprothesis. En: Tasman W, Jaeger EA (eds.). Duane’s Clinical Ophthalmology. 22nd ed. Philadelphia: Lippincott Williams & Wilkins; 1998, p. 1-6.

  5. França ET, Arcieri ES, Arcieri RS, Rocha FJ. A study of glaucoma after penetrating keratoplasty. Cornea 2002; 21: 284-8.

  6. Panel de Expertos en Glaucoma. Diagnóstico. En: Lineamientos y Recomendaciones para el Manejo del Glaucoma. 2a. Ed. México: Intersistemas Editores; 2000, p. 2-25.

  7. Ayyala RS. Penetrating keratoplasty and glaucoma. Surv Ophthalmol 2000; 45: 91-105.

  8. Dada T, Agarwal A, Minudath KB, Vanathi M, Choudary S, Gupta V, et al. Post-penetrating keratoplasty glaucoma. Indian J Ophthalmol 2008; 56: 269-77.

  9. Karadag O, Kugu S, Erdogan G, Kandemir B, Ozdil SE, Dogan OK. Incidence and risk factors for increased intraocular pressure after penetrating keratoplasty. Cornea 2010; 29: 278-82.

  10. Allouch C, Borderie V, Touzeau O, Scheer S, Nordmann JP, Laroche L. Incidence et facteurs de risque de l’hypertonie oculaire au cours des kératoplasties transfixiantes. J Fr Ophthalmol 2003; 26: 553-61.

  11. Rumelt S, Bersudsky V, Blum-Hareuveni T, Rehany U. Preexisting and postoperative glaucoma in repeated corneal transplantation. Cornea 2002; 21: 759-65.

  12. De Freitas AM, Melo BC, Mendonça CN, Machado RP, Rocha FJ. Causes and risk factors for graft failure in surgeries performed by physicians in fellowship training. Cornea 2006; 25: 251-6.

  13. Bertelmann E, Peleyer U, Rieck P. Risk factors for endothelial cell loss post-keratoplasty. Act Ophthalmol Scadinav 2006; 84: 766-70.

  14. Mc Neil JI. Indications and outcomes. In: Krachmer JH, Mannis MJ, Holland EJ. Cornea. 2nd ed. London: Elsevier Health Sciences; 2005, p. 1420-1.

  15. Guzmán-Jiménez LK, Beauregard-Escobar AM, Ballesteros de la Torre F. Frecuencia de las patologías relacionadas con rechazo a transplante de córnea en pacientes con queratoplastia penetrante. Rev Mex Oftalmol 2006; 325-9.

  16. Vanathi M, Sharma N, Sinha R, Tandon R, Titiyal JS, Vajpayee RB. Indications and outcome of repeat penetrating keratoplasty in India. BMC Ophthalmol 2005; 5: 26.

  17. Patel SV, Hodge DO, Bourne WM. Corneal endothelium and postoperative outcomes 15 years after penetrating keratoplasty. Am J Ophthalmol 2005; 139: 311-9.

  18. Shemesh G, Waisbourd M, Varssano D, Michaeli A, Lazar M, Kurtz S. Measurements of intraocular pressure by Goldmann Tonometry, Tonopen XL and the transpalpebral tonometer, TGDc-01, after penetrating keratoplasty: a comparative study. Cornea 2009; 28: 724-7.

  19. Moreno-Montañés J, Olmo N, Zarranz-Ventura J, Heras-Mulero H. Dynamic contour tonometry in eyes after penetrating keratoplasty. Cornea 2009; 28: 836-7.

  20. Chua J, Mehta JS, Tan DTH. Use of anterior segment optical coherence tomography to assess secondary glaucoma after penetrating keratoplasty. Cornea 2009; 28: 243-5.

  21. Dada T, Aggarwal A, Vanathi M, Gadia R, Panda A, Gupta, et al. Ultrasound biomicroscopy in opaque grafts with post-penetrating keratoplasty glaucoma. Cornea 2008; 27: 402-5.

  22. Rojas-Álvarez E, Méndez-Duque-de-Estrada A, González- Sotero J, Casanueva-Cabeza HC, Alberro-Hernández M. Hipertensión ocular posqueratoplastia. Rev Mex Oftalmol 2010; 84: 30-3.

  23. Seitz V, Lagenbucher A, Nguyen NX, Küchle M, Naumann GOH. Long term follow-up of intraocular pressure after penetrating keratoplasty for keratoconus and Fuch´s dystrophy. Cornea 2002; 21: 368-73.




2020     |     www.medigraphic.com