2013, Number 1
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Rev Med Inst Mex Seguro Soc 2013; 51 (1)
Sensitivity and specificity of a utility model of the detection of diabetic neuropathy
Mendoza-Romo MÁ, Ramírez-Arriola MC, Velasco-Chávez JF, Nieva-de Jesús RN, Rodríguez-Pérez CV, Valdez-Jiménez LÁ
Language: Spanish
References: 19
Page: 34-41
PDF size: 279.83 Kb.
ABSTRACT
Objective: to determine whether a utility model can be used with acceptable sensitivity and specificity for the diagnosis of diabetic peripheral neuropathy (DPN).
Methods: cross sectional study, non-probability sampling, in 381 type 2 diabetic patients with diabetic foot risk. To determine the DPN, it was evaluated the protective sensation in 10 sites on the foot. It was a positive diagnosis if three or more points showed insensitivity at the touch of the skin with Semmes-Weinstein monofilament (SWM). Monofilament was compared to the utility model (MMU); the diagnostic methods of application were the same for both.
Results: mean age was 62 years, 11 years of development of DM, mean body mass index of 29 kg/m
2, average glucose 129 mg/dL (78-264 mg/dL). With sensitivity of 73.68 %, 97.67 % of specificity, positive predictive value 77.78 %, negative predictive value 97.10 %, the positive likelihood ratio was 31.59 and the negative likelihood ratio 0.27.
Conclusion: currently, diagnostic devices for tactile sensory loss are not readily available in our country; therefore, the results of this research will help to make the diagnosis of the MMU timely, inexpensive and easily accessible.
REFERENCES
Tan LS. The clinical use of the 10g monofilament and its limitations: a review. Diabetes Res Clin Pract. 2010;90(1):1-7. Epub 2010/07/27.
World Healt Organization. Diabetes fact sheet. [Consultado el 19 julio del 2011]. Disponible en http://www.who.int/mediacentre/factsheets/fs312en/
Wu SC, Driver VR, Wrobel JS, Armstrong DG. Foot ulcers in the diabetic patient, prevention and treatment. Vasc Health Risk Manag. 2007;3(1):65-76.
Dros J, Wewerinke A, Bindels PJ, van Weert HC. Accuracy of monofilament testing to diagnose peripheral neuropathy: a systematic review. Ann Fam Med. 2009;7(6):555-8.
Boulton AJ, Vileikyte L, Ragnarson-Tennvall G, Apelqvist J. The global burden of diabetic foot disease. Lancet. 2005;366(9498):1719-24.
Valk GD, Kriegsman DM, Assendelft WJ. Patient education for preventing diabetic foot ulceration. Cochrane Database Syst Rev. 2005;(1):CD001488.
Mendoza-Romo M, Ramírez-Arriola M. Abordaje multidisciplinario del pie diabético. Rev Endocrinol Nutr. 2005;13(4):165-79.
Singh N, Armstrong DG, Lipsky BA. Preventing foot ulcers in patients with diabetes. JAMA. 2005;293(2):217-28.
Feno Y, Schlosser FJ, Sumpio BE. The Semmes Weinstein monofilament examination is a Significant predictor of the risk or foot ulceration and amputation in patients with diabetes mellitus. J Vasc Surg. 2011;53(1):220-6 e1-5. Epub 2010 Aug 8.
Jayaprakash P, Bhansali A, Bhansali S, Dutta P, Anantharaman R, Shanmugasundar G. et al. Validation of bedside methods in evaluation ol diabetic peripheral neuropathy. lndian J Med Res. 2011; 133(6):645-9.
Pham H, Armstrong DG, Harvey C, Harkless LB, et al Screening techniques to identify people at high risk for diabetic foot ulceration: a prospective multicenter trial Diabetes Care. 2000;23(5):606-11.
American Diabetes Association. Standards of medical care in diabetes 2011. Diabetes Care. 2011;34 Suppl 1:S11-61.
Norma oficial mexicana NOM-015-SSA2-1994, para la prevención, tratamiento y control de la diabetes mellitus en la atención primaria. Disponible en http://www.salud.gob.mx/unidades/cdiLnom015ssa.24html
Instituto Mexicano del Seguro Social. Guia de práctica clínica para el diagnóstico y tratamiento de la diabetes mellitus tipo 2 en el primer nivel de atención. México: IMSS; 2009.
Lee S, Kim H, Choi S, Park Y, Kim Y, Cho B. Clinical usefulness of the two-site Semmes-Weinstein monofilament test for detecting diabetic peripheral neuropathy. J Korean Med Sci. 2003;18(1):103-7.
Booth J, Young MJ. Differences in the performance of commercially available 10-g monofilaments. Diabetes care. 2000;23(7):984-8.
Mayfield JA, Sugarman JR. The use of the Semmes- Weinstein monofilament and other threshold tests for preventing foot ulceration and amputation in persons with diabetes. J Fam Pract. 2000;49(11 Suppl):S17-29.
Armstrong DG. The 10-g monofilament: the diagnostic divining rod for the diabetic foot? Diabetes care. 2000;23(7):887.
Ministerio de Sanidad y Consumo. Guía de práctica clínica sobre diabetes tipo 2. España: Ministerio de Sanidad y Consumo; 2008.