Rentería AMC, Zetina THJ, Ballesteros LHJ

Language: Spanish
References: 15
Page: 156-161
PDF size: 62.95 Kb.

ABSTRACT

Objective: To study the protective effects of L-carnitine in patients undergoing to open cardiac surgery. Design: Controlled, double-blind study. Setting: Cardiovascular postoperative ICU (UTIPX) of a tertiary care hospital, México City. Patients: Thirty patients (group I, mean age 56.9 yrs) and twenty patients (group II, mean age 56.6 yrs) undergoing to cardiac surgery and cardiopulmonary bypass (CPB). Interventions: Twelve hours before surgery group I received a placebo and group II 1 g of L-carnitine; an additional dose of placebo and L-carnitine was given at the beginning of CPB. Measurements and main results: The use of drugs, anormal postoperative ECG’s, postoperative serum level of CPK, cardiac failure and postoperative complications were less important in the L-carnitine group (p ‹ 0.05). Conclusion: L-carnitine reduces the deleterious conse-quences of CPB in patients undergoing to heart surgery.

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