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Instituto Nacional de Neurología y Neurocirugía

2012, Number 4

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Arch Neurocien 2012; 17 (4)

Prions: update and review of the handling of surgical brain biopsies

Hernández SM, Zarate-Méndez A, Ruiz y Cuéllar LE, Lucino-Castillo J, Lujan-Guerra J, Franco-Téllez JJ, Martínez-Escobar C, del Rio-Mendoza ED

Language: Spanish
References: 14
Page: 234-241
PDF size: 172.82 Kb.


ABSTRACT

Update the knowledge about particles called prions, handling precautions and recommendations of tissue in patients with suspected infection, in addition to a systematization of the item has slopes of great medical interest. We reviewed studies of the last 10 years systematically with keywords that included, prion, orCreutzfeldtdakob spongiform encephalopathy, dementia and brain biopsy progression fast. In Mesh Ime&line), human papers were included in English and Spanish domains. We perlormed a screening of the work that made mention of experience (more than onol and that related to the handling precautions and tissues of patients with spongiform encephalopathy. Consistent with the literature, patients with probable prion disease should be treated with great caution, first to see if there is possibility brain biopsy to confirm the diagnosis, and after his death according to European recommendations mainly in the preparation of cremation. The sporadic appearance of disease is spontaneous, the prion protein remains a major source of molecular research has generated two novel awards. Not everything has been linked to disease just as there are approaches that knowledge of the foundations of learning is linked to prions according to faculty experts like Professor Eric R. Kandel.


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