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Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

2011, Number 2

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Rev Invest Clin 2011; 63 (2)

Trends of thyroid pathology in a referral center: Steady prevalence of papillary thyroid carcinoma but goiter increase in thyroidectomies

Gamboa-Domínguez A, Lino-Silva S, Candanedo-González F, Medina-López E, Acuña-González D, Jacinto-Cortés i, González-Treviño O

Language: Spanish
References: 28
Page: 148-154
PDF size: 87.10 Kb.


ABSTRACT

Introduction. Changes in the prevalence of papillary thyroid carcinoma (PTC) have been reported in institutions and national cancer registries. Objective. To describe time trends in benign and malignant thyroid diseases in a national endocrine referral center. Materials and methods. Systematic review and classification of consecutive specimens with slides/paraffin blocks in surgical pathology archives (January 1990 to December 2009). Institutional registries, size, type of surgery and number of inclusion blocks were recorded. Patients whose registries were granted before January 1990 without nodules, but treated after twelve months for a suspicious thyroid lesion, were included. These patients in a passive follow-up permitted incidence density calculations. Cases were grouped by quinquennium. Results. Institutional registers were conceded to 103,961 persons worthy of attention, and 1,269 were submitted to thyroidectomies (1.2%). One hundred twenty four patients none treated for thyroid diseases before 1990, developed thyroid nodules after 1991. The incidence density for goiter was 0.05 person/year and for PTC 0.04 person/year in that group. In all series woman to man relation was 9:1 with a mean age of 45 years. Total or near total thyroidectomies were performed in 60% patients and benign diseases were diagnosed in 732 (52%) cases. Thyroid surgeries increased since 2005 (p = 0.03) with a rise in goiter prevalence (0.25, 0.31, 0.35, 0.38, p for trend 0.0005), without significant increase in PTC prevalence (0.41, 0.43, 0.35, 0.40, p for trend 0.71) in thyroidectomies. Conclusions. Goiter as the only finding in thyroid specimens increased 52% in the last 20 years. PTC prevalence is steady with a higher number of tumors ‹ 3 cm.


REFERENCES

  1. López LH, Canto JA, Herrera MF, et al. Efficacy of fine-needle aspiration biopsy of thyroid nodules. Experience of a Mexican institution. World J Surg 1997; 21: 408-11.

  2. Raber W, Kaserer K, Niederle B, Vierhapper H. Risk factors for malignancy of thyroid nodules initially identified as follicular neoplasia by fine-needle aspiration: results of a prospective study of one hundred twenty patients. Thyroid 2000; 10: 709-12.

  3. Papini E, Guglielmi R, Bianchini A, et al. Risk of malignancy in non palpable thyroid nodules: Predictive values of ultrasound and color Doppler features. J Clin Endocrinol Metab 2002; 87: 1941-6.

  4. Ross DS. Predicting thyroid malignancy. J Clin Endocrinol Metab 2006; 91: 4253-5.

  5. dos Santos Silva I, Swerdlow AJ. Thyroid cancer epidemiology in England and Wales: time trends and geographical distribution. Br J Cancer 1993; 67: 330-40.

  6. Burgess JR, Dwyer T, McArdle K, et al. The changing incidence and spectrum of thyroid carcinoma in Tasmania (1978- 1998) during a transition from iodine sufficiency to iodine deficiency. J Clin Endocrinol Metab 2000; 85: 1513-17.

  7. Liu S, Semenciw R, Ugnat A-M, Mao Y. Increasing thyroid cancer incidence in Canada, 1970-1996: time trends and ageperiod- cohort effects. Br J Cancer 2001; 85: 1335-9.

  8. Colonna M, Grosclaude P, Remontet L, et al. Incidence of thyroid cancer in adults recorded by French cancer registries (1978-1997). Eur J Cancer 2002; 38: 1762-8.

  9. Reynolds R, Weir J, Stockton DL, et al. Changing trends in incidence and mortality of thyroid cancer in Scotland. Clin Endocrinol 2005; 62: 156-62.

  10. Leenhardt L, Bernier MO, Boin-Pineau MH, et al. Advances in diagnostic practices affect thyroid cancer incidence in France. Eur J Endocrinol 2004; 150: 133-9.

  11. Davies L, Welch HG. Increasing incidence of thyroid cancer in the United States, 1973-2002. JAMA 2006; 295: 2164-7.

  12. Lin JD, Chao TC, Huang BY, et al. Thyroid cancer in the thyroid nodules evaluated by ultrasonography and fine-needle aspiration cytology. Thyroid 2005; 15: 708-17.

  13. Niedziela M, Korman E, Breborowicz D, et al. A prospective study of thyroid nodular disease in children and adolescents in western Poland from 1996 to 2000 and the incidence of thyroid carcinoma relative to iodine deficiency and the Chernobyl disaster. Med Pediatr Oncol 2004; 42: 84-92.

  14. Candadeno-Gonzalez FA, Gamboa-Dominguez A. The many faces of papillary thyroid carcinoma. In: Camacho-Arroyo I (Ed.). Advances in selected topics in endocrinology. Research signpost; 2009, p. 257.

  15. Lubina A, Cohen O, Barchana M, et al. Time trends of incidence rates of thyroid cancer in Israel: What might explain the sharp increase? Thyroid 2006; 16: 1033-40.

  16. Scheiden R, Keipes M, Bock C, et al. Thyroid cancer in Luxembourg: a national population-based data report (1983- 1999). BMC Cancer 2006; 6: 102.

  17. Steliarova-Foucher E, Stiller CA, Pukkala E, et al. Thyroid cancer incidence and survival among European children and adolescents (1978-1997): Report from the automated childhood cancer information system project. EJC 2006; 42: 2150-69.

  18. Kent WDT, Hall SF, Isotalo PA, et al. Increases incidence of differentiated thyroid carcinoma and detection of subclinical disease. CMAJ 2007; 177: 1357-61.

  19. Colonna M, Guizard AV, Schvartz C, et al. A time trend analysis of papillary and follicular cancers as a function of tumor size: A study of data from six cancer registries in France (1983-2000). EJC 2007; 43: 891-900.

  20. Disponible en: http://www.dgepi.salud.gob.mx Julio 2010.

  21. García Rodríguez H, Madrid Franco R, Ramírez Zepeda G. Prevalencia de cáncer tiroideo en postoperados de tiroides. A S Sin 2008; II: 8-11.

  22. Rego Ireta A, Pérez Méndez LF, Mantinan B, García Mayor RB. Time trends for thyroid cancer in northwestern Spain: True rise in the incidence of micro and larger forms of papillary thyroid carcinoma. Thyroid 2009; 19: 333-40.

  23. Hurtado López LM, Zaldivar Ramírez FR, Pulido Cejudo A, et al. Criterios clínicos de malignidad en el nódulo tiroideo ¿Están vigentes? Cir Gen 2001; 23: 25-8.

  24. Madrid Franco JR, Baquera Heredia J, Herrera H, Aguirre Niebla A, et al. Cáncer de tiroides en la principal zona bociogena de México. Cir Gen 1999; 21: 31-4.

  25. Albores-Saavedra J, Henson DE, Glazer E, Schwartz AM. Changing patterns in the incidence and survival of thyroid cancer with follicular phenotype –Papillary, follicular and anaplastic: A morphological and epidemiological study. Endocr Pathol 2007; 18: 1-7.

  26. Herrera MF, López CM, Saldaña J, et al. Evolución de la cirugía de tiroides en el Instituto Nacional de la Nutrición Salvador Zubirán. Rev Invest Clin 1995; 47: 13-19.

  27. Utiger RD. The multiplicity of thyroid nodules and carcinomas. N Engl J Med 2005; 352: 2376-8.

  28. Larraza Hernández O. La autopsia en la epidemiología de las neoplasias malignas. En: Meneses García A, Mohar Betancourt A (Eds.). Principales neoplasias malignas en México. Manual Moderno; 1999, p. 7-16.




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