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2013, Number 1

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Acta Med 2013; 11 (1)

Kaposi’s sarcoma: literature review and illustration of a case

Rojo EA

Language: Spanish
References: 52
Page: 23-31
PDF size: 118.72 Kb.


ABSTRACT

Kaposi’s sarcoma is a mesenchymal tumor with involvement of blood vessels and lymphatics, caused by Human herpesvirus 8, also known as Kaposi’s sarcoma-associated herpesvirus. It was originally described by Moritz Kaposi, a hungarian dermatologist at the University of Vienna in 1872. It became more widely known as one of the AIDS defining illnesses since the 80’s. The viral cause for this cancer was discovered until 1994. Kaposi’s sarcoma is a systemic disease that can present with cutaneous lesions with or without internal involvement. Four subtypes have been described: classic Kaposi’s sarcoma, affecting middle aged men of Mediterranean and Jewish descent; African endemic Kaposi’s sarcoma; Kaposi’s sarcoma in iatrogenically immunosuppressed patients; and AIDS-related Kaposi’s sarcoma. Once the diagnosis of Kaposi’s sarcoma has been made, treatment is based on the subtype and the presence of localized versus systemic disease. This article provides an overview of epidemiology, subtypes, clinical course, pathogenesis, and management strategies for Kaposi sarcoma and the presentation of a clinical case.


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