Maya QJJ, Zúñiga LDS, Maya QJL

Idioma: Español
Referencias bibliográficas: 41
Paginas: 17-22
Archivo PDF: 72.47 Kb.

RESUMEN

La colestasis intrahepática del embarazo es una forma reversible de colestasis que se presenta durante el segundo y tercer trimestres de la gestación. Se caracteriza por prurito generalizado que predomina en palmas y plantas, acompañado de una elevación en los niveles séricos de ácidos biliares. No implica un riesgo materno; sin embargo, existe un aumento en el riesgo de desenlaces fetales adversos, principalmente el nacimiento pretérmino, líquido amniótico meconial y muerte in utero. A pesar de que el ácido ursodesoxicólico ha demostrado ser eficaz, no se ha logrado la disminución de estos desenlaces y tampoco existe un método de vigilancia fetal ideal para estos casos. El presente artículo tiene como propósito la revisión de la literatura, así como la presentación de un caso de una paciente de 32 años con antecedente de dos óbitos fetales de etiología desconocida. Durante la semana 30.2 de la última gestación presentó prurito en palmas y plantas acompañado de discreta ictericia generalizada. Se tuvo sospecha de colestasis intrahepática del embarazo por el cuadro clínico y las cifras séricas de ácidos biliares elevadas.

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