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2013, Number 1

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Rev cubana med 2013; 52 (1)

Influence of infection by the hepatitis C virus on mortality in hemodialysis patients

Capote PL, Mora GS, Joseph PH, Herrera AM, González RM, Moret HY

Language: Spanish
References: 37
Page: 25-36
PDF size: 158.03 Kb.


ABSTRACT

Introduction: hepatitis C remains a health problem in hemodialysis centers.
Methods: a historical cohort study was conducted. 215 patients who entered Dr. Luis Díaz Soto Military Hospital hemodialysis center from 1995 to 2008 were included. Isolation criteria of patients with hepatitis C were considered as exposure periods.
Results: overall mortality was 30.2%, lethality and mortality from hepatitis C were higher in the exposure period (53.8% and 16.6%, respectively). In multivariate analysis by Cox regression, the presence of hepatitis C and treatment with hemodialysis were observed to be death risk factors in a shorter time of observation, during periods of increased incidence (p = 0.014), regardless of the burden of comorbidities.
Conclusions: HCV infection in patients on hemodialysis contributes to increased mortality even when taking into account the burden of comorbidities.


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