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2013, Número 1

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Rev cubana med 2013; 52 (1)


Influencia de la infección por el virus de la hepatitis C en la mortalidad de los pacientes en hemodiálisis

Capote PL, Mora GS, Joseph PH, Herrera AM, González RM, Moret HY

Idioma: Español
Referencias bibliográficas: 37
Paginas: 25-36
Archivo PDF: 158.03 Kb.


RESUMEN

Introducción: la hepatitis C se mantiene como un problema de salud en los centros de hemodiálisis.
Métodos: se realizó un estudio de cohorte histórico donde se incluyeron 215 pacientes que ingresaron al centro de hemodiálisis del Hospital Militar "Dr. Luis Díaz Soto", entre 1995 y 2008. Se tomaron como períodos de exposición los criterios de aislamiento de pacientes con hepatitis C.
Resultados: se halló mortalidad general de 30,2 %, la letalidad y la mortalidad por hepatitis C fueron mayores en el período de exposición con 53,8 % y 16,6 %, respectivamente. En el análisis multivariado por regresión de Cox se observó que constituyeron factores de riesgo de morir, en un menor tiempo de observación, la presencia de hepatitis C y recibir tratamiento con hemodiálisis en los períodos de mayor incidencia (p=0,014), independientemente de la carga de comorbilidades.
Conclusiones: la infección por el VHC contribuye a aumentar la mortalidad de los pacientes en tratamiento con hemodiálisis, cuando se tiene en cuenta la carga de comorbilidades.


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