2013, Number 1
<< Back Next >>
Bol Med Hosp Infant Mex 2013; 70 (1)
Diffuse neonatal hemangiomatosis
Maya J, Blanco G, Maldonado R
Language: Spanish
References: 11
Page: 38-43
PDF size: 252.38 Kb.
ABSTRACT
Introduction. Diffuse neonatal hemangiomatosis is a rare entity and is a serious disorder in which multiple cutaneous and visceral hemangiomas are widely distributed and sometimes may be fatal. Complications include heart failure, bleeding, and liver failure, among others. Treatment is aimed at avoiding adverse effects and complications.
Case report. We report the case of a 53-day-old male patient who presented to the hospital for skin lesions and upper gastrointestinal bleeding. During his hospital stay, visceral hemangiomas were found in the lung, spleen and gastric mucosa. He was treated with interferon alpha-2b corticosteroids and hemangiomas of gastric mucosa were treated with argon plasma coagulation.
Conclusions. Disseminated neonatal hemangiomatosis is a rare entity and can be fatal if untreated. Our patient experienced a satisfactory evolution and is currently asymptomatic.
REFERENCES
Lister WA. The natural history of strawberry naevi. Lancet 1938;1:1429-1434.
Metry DW, Hebert AA. Benign cutaneous vascular tumors of infancy: when to worry, what to do. Arch Dermatol 2000;136:905-914.
Ohnishi S, Miyagishima T, Nakagawa M, Kamata T, Kishimoto A, Choi GH, et al. Diffuse neonatal hemangiomatosis without cutaneous lesions in an adult-a case report. Angiology 2002;53:235-237.
Mulliken JB, Glowacki J. Hemangiomas and vascular malformations in infants and children: a classification based on endothelial characteristics. Plast Reconstr Surg 1982;69:412-420.
Ollague J. Hemangiomatosis neonatal difusa. Folia Dermatol Peru 2007;18:28-31.
Gottschling S, Schneider G, Meyer S, Reinhard H, Dill-Mueller D, Graf N. Two infants with life-threatening diffuse neonatal hemangiomatosis treated with cyclophosphamide. Pediatr Blood Cancer 2006;46:239-242.
Wananukul S, Voramethkul W, Nuchprayoon I, Seksarn P. Diffuse neonatal hemangiomatosis: report of 5 cases. J Med Assoc Thai 2006;89:1297-1303.
Enjolras O, Brevière GM, Roger G, Tovi M, Pellegrino B, Varotti E, et al. Vincristine treatment for function -and life- threatening infantile hemangioma. Arch Pediatr 2004;11:99-107.
Mazereeuw-Hautier J, Hoeger PH, Benlahrech S, Ammour A, Broue P, Vial J, et al. Efficacy of propranolol in hepatic infantile hemangiomas with diffuse neonatal hemangiomatosis. J Pediatr 2010;157:340-342.
Vlahovic A, Simic R, Djokic D, Ceran C. Diffuse neonatal hemangiomatosis treatment with cyclophosphamide: a case report. J Pediatr Hematol Oncol 2009;31:858-860.
Khan K, Schwarzenberg SJ, Sharp H, Weisdorf-Schindele S. Argon plasma coagulation: clinical experience in pediatric patients. Gastrointest Endosc 2003;57:110-112.