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2000, Number 4

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Arch Cardiol Mex 2000; 70 (4)

Infective endocarditis in intravenous drug addicts

Aguilar JA, Summerson C

Language: Spanish
References: 36
Page: 384-390
PDF size: 285.96 Kb.


ABSTRACT

Infective endocarditis is a frequent complication in intravenous drugs abusers. It is evident that in recent years this problem has increases as a consequence of the growing number of drug addicts. We review the clinical files of patients who entered the Regional General Hospital No. 20 IMSS in the City of Tijuana Mexico between May 1994 and May 1998 with diagnosis of infective endocarditis and had evidence intravenous abuse. Eight patients were included in the study. None of them had preexisting valve abnormalities. The infection involved right-sided values in 62.5% of cases left-sided values in 12.5%, and both sides in 12.5% of cases Staphylococcus aureus was the infecting germ in 50% of the cases. Survival of patients with right infective endocarditis was 75% and only 25% of them required surgical intervention. The mortality of infection in left side was 75% and 100% if infection involved both sides. Infective endocarditis in drugs abusers has a favorable prognosis when right sided valves are affected. Mortality rates are higher in patients with left-sided involvement.


REFERENCES

  1. Reisberg BE: Infective endocarditis in the narcotic addict. Prog Cardiovase Dis 1979; 22: 193-204.

  2. Luttgens WL: Favorable experience with bacterial endocarditis in heroin addicts. Ann Intern Med 1973; 78: 25-32.

  3. Ramsey RG, Gunnar RM, Tobin JR: Endocarditis in the drug addict. Am J Cardiol 1970; 25: 608-618.

  4. Menda KB, Gorbach SL: Favorable experience with bacterial endocarditis in heroin addicts. Ann Intern Med 1973; 78: 25-32.

  5. Dreyer NP, Field BN: Heroin-associated infective endocarditis. A report of 28 cases. Ann Intern Med 1973; 78: 699-702.

  6. Banks T, Fletcher R, Ali N: Infective endocarditis in heroin addicts. Am J Med 1973; 55: 444-451.

  7. Curtis J, Richman BL, Fenstein MA: Infective endocarditis in drug addicts. South Med J 1974; 67: 4-9.

  8. Lange M, Salaki JS, Middleton JR: Infective endocarditis in heroin addicts: epidemiological observations and some unusual cases. Am Heart J 1978; 96: 144-152.

  9. Scheidegger C, Zimmerl W: Infectious complications in drug addicts: Seven-year review of 269 hospitalized narcotics abusers in Switzerland. Rev Infect Dis 1989; 11: 486-492.

  10. Hecht SR, Berger M: Right-sided endocarditis in intravenous drug users. Prognostic features in 102 episodes. Ann Intern Med 1992; 117: 560-566.

  11. Roberts WC, Buchbinder NA: Healed left-sided infective endocarditis: a clinicopathologic study of 59 patients. Am J Cardiol 1977; 40: 876-888.

  12. Buchbinder NA, Roberts WC: Left-sided valvular active infective endocarditis. A study offorty-five necropsypatients. Am J Cardiol 1972; 53: 20-35.

  13. CA Souto Meiriño, LE Cotter Lemus, J Assad Gutierrez, et al: Endocarditis Infecciosa en el Instituto Nacional de Cardiología “Ignacio Chavez” Experiencia de cinco años (1990-1994). Arch Inst Cardiol Mex 1997; 67: 46-50.

  14. Durack DT, Lukes AS, Bright DK, and the Duke Endocarditis Service: New Criteria for diagnosis of infective endocarditis: utilization of specific echocardiographic findigs. Am J Med 1994; 96: 200-209.

  15. Clemens JD, Horwitz RI, Jaffee CC, et al: A controlled evaluation of the risk of bacterial endocarditis in people with mitral valve prolapse. N Engl J Med 1982; 307: 776-780.

  16. McKinsey DS, Ratts TE, Bisno AL: Underlying cardiac lesions in adults with infective endocarditis. The changing spectrum. Am J Med 1987; 82: 681-687.

  17. Weinberger I, Rotenberg Z, Zacharovitch D, Fuchs J, Davidson E, Agmon J: Native valve endocarditis in the 1970’s versus the 1980’s: Underlying cardiac lesions and infecting organisms. Clin Cardiol 1990; 13: 94-101.

  18. De Rosa A, Botvinik G, Kaufman S: Infective endocarditis and drug addiction. Medicina B Aires 1994; 54: 193-198.

  19. Benn M, Hagelskjaer LH, Tvede M: Infective endocarditis, 1984 through 1993: a clinical and microbiological survey. J Intern Med 1997; 242: 15-22.

  20. Chambers HF, Morris DL, Tauber MG, et al: Cocaine use and the risk for endocarditis in intravenous drug users. Ann Intern Med 1987; 106: 833-837.

  21. Eichacker PQ, Miller K Robbins M, et al: Echocardiographic evaluation of heart valves in IV drugs abusers without a previous history of endocarditis. Clin Res 1984; 32: 670A-674A.

  22. Chambers HG, Korzeniowski OM, Sande MA: The National Collaborative Endocarditis Study Group. Staphylococcus aureus endocarditis: clinical manifestation in addicts and noaddicts. Medicine 1983; 62: 170-177.

  23. Tuazon CW, Sheagren JW: Increased rate of carriage of Staphylococcus aureus among narcotic addicts. J Infect Dis 1974; 129: 725-28.

  24. Andriole VT, Kravetz HM, Roberts WC: Candida endocarditis. Clinical and pathologic studies. Am J Med 1962; 32: 251-85.

  25. Saravolatz LD, Burch KH, Quinn EL: Polymicrobial infective endocarditis. An increasing clinical entity. Am Heart J 1978; 95: 163-165.

  26. Julander I: Staphylococcal septicemia and endocarditis in 80 drug addicts. Aspects on epidemiology, clinical and laboratory findings and prognosis. Scan J Infect Dis 1983; 41(suppl): 49-58.

  27. Baddour LM: Twelve year review of recurrent native valve infective endocarditis. A disease of the modern antibiotic era. Rev Infects Dis 1988; 10: 1163-1175.

  28. Dressler FA, Roberts WC: Infective endocarditis in opiate addicts: Analysis of 80 cases studied at necropsy. Am J Cardiol 1989; 63: 1240-1257.

  29. Stromm JA, Frishman WH, Klein N: Effect of vegetation size on the autcome of patients with infective endocarditis (Abstr). Circulation 1982; 66: 103.

  30. Manolis AS, Melita H: Echocardiographic and clinical correlates in drug addicts with infective endocarditis. Implications of vegetation size. Arch Intern Med 1988; 148: 2461-2465.

  31. Wong D, Chundraratha AN, Wishnow RM: Clinical vegetations in infections endocarditis. Arch Med 1983; 143: 1874-1881.

  32. Ginzton LE, Siegel RJ, Criley: Natural history of tricuspid valve endocarditis. A two dimentional echocardiographic study. Am J Cardiol 1982; 49: 1853-1859.

  33. Berger M, Delfin L, Jelveh M, et al: Two-dimensional echocardiographic findings in right-sided infective endocarditis. Circulation 1980; 61: 855-61.

  34. Abrams B, Sklaver A, Hoffman T, et al: Single or combination teraphy of Staphylococcal endocarditis in intravenous abusers. Ann Intern Med 1979; 90: 789-791.

  35. Robin EK, Thomas NW, Arbulu A: Hemodynamic consequences of total removal of the tricuspid valve without prosthetic replacement. Am J Cardiol 1975; 35: 481-486.

  36. DiNubile M: Surgery for addiction-related tricuspid valve endocarditis: Caveat emptor. Am J Med 1987; 82: 811-813.




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