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ISSN 0188-9796 (Print)

2012, Number 2

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Rev Endocrinol Nutr 2012; 20 (2)

Treatment of neuropathic pain with gabapentin combined with vitamins B1 and B12. A prospective observational study

Sánchez CV, González HC, Aguilar GA, Torres GRA

Language: Spanish
References: 19
Page: 67-73
PDF size: 388.16 Kb.


ABSTRACT

Objective: To document the efficacy and safety of the combination gabapentin plus vitamins B1 and B12. Method: A prospective, observational, longitudinal, multicenter study, in patients with neuropathic pain treated with gabapentin plus vitamins B1 and B12 for a month. Efficacy, quality of life, and safety were evaluated. Statistical analysis consisted in descriptive and inferential statistics. Results: There were 1,757 patients in the study. Neurological and gastrointestinal were the most common adverse reactions. Only 8 patients had 23 serious adverse events. Combination showed efficacy to reduce the intensity of pain and improved quality of life. Conclusions: This study showed that combination of gabapentin plus vitamins B1 and B12 reduce neuropathic pain and improve the quality of life with an excellent safety profile.


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