2012, Number 6
<< Back Next >>
Rev Mex Urol 2012; 72 (6)
Renal leiomyosarcoma
Zamora-Varela FR, Ponce-de León BF
Language: Spanish
References: 11
Page: 297-300
PDF size: 224.21 Kb.
ABSTRACT
Renal leiomyosarcoma is a rare and aggressive pathology that makes up 2% of renal tumors in the adult, presenting in the fifth and sixth decades of life. Diagnosis is made
through abdominal computerized tomography (CAT) or magnetic resonance imaging (MRI). Radical nephrectomy is the treatment of choice and outcome is poor.
A 32-year-old man presented with pain in the left renal fossa, gross hematuria, weight loss, and a palpable abdominal mass. CAT scan revealed a left renal tumor for which radical nephrectomy was performed. The histopathologic
study reported poorly differentiated leiomyosarcoma with a high grade of malignancy. Treatment based on chemotherapy and radiotherapy was successful.
Leiomyosarcomas are tumors of aggressive progression. Radical nephrectomy, which is the treatment of choice, plus adjuvant chemotherapy and radiotherapy is a therapeutic option.
REFERENCES
Dhawan S, Chopra P, Dhawan S. Primary renal leiomyosarcoma: A diagnostic challenge. Urol Ann 2012;4(1):48-50.
Srinivas V, Sogani PC, Hajdu SI, et al. Sarcomas of the kidney. J Urol 1984;132(1):13-16.
Thrasher JB, Paulson DF. Prognostic factors in renal cancer. Urol Clin North Am 1993;20(2):247-262.
Steiner G, Cairns P, Polascik TJ, et al. High-density mapping of chromosomal arm 1q in renal collecting duct carcinoma: Region of minimal deletion at 1q32.1–32 2. Cancer Res 1996;56(21):5044- 5046.
Steiner M, Quinlan D, Goldmann SM, et al. Leiomyoma of the kidney: Presentation of 4 new cases and the role of computerized tomography. J Urol 1990;143(5):994-998.
Venkatesh K, Lamba Saini M, Niveditha SR, et al. Primary Leiomyosarcoma of the kidney. Patholog Res Int 2010;2010:652398.
Swee–Kok L, Tinckler LF. Leiomyosarcoma of the kidney a case report. Singapore Med J 1971;12(2):114-119.
Kendal WS. The comparative survival of renal leiomyosarcoma. Can J Urol 2007;14(1):3435-3442.
Argüelles-Salido E, Medina-López RA, Congregado-Ruiz CB, et al. Análisis de las neoplasias renales en adultos menores de 40 años. Actas Urol Esp 2004;28(5):335-340.
Clemente Ramos LM, Candia Fernández A, Allona Almagro. Leiomioma renal sintomático: una masa renal de difícil diagnóstico. Actas Urol Esp 2003;27(7):546-550.
Martínez-Cornelio A, Ramos-Salgado F, Hernández-Ramírez D, et al. Leiomiosarcoma renal. Informe de un caso. Cirugía y Cirujanos 2011;79:282-285.
Full text