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2011, Number 2

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Rev Med MD 2011; 2.3 (2)

Visceral Leishmaniasis and Mycobacterium tuberculosis in a patient with AIDS in Mexico

Manríquez-Reyes M, Chable-Montero F, Gamboa-Domínguez A, Estradas-Trujillo JA, Chávez-Mazari B, Ingerborg B, Pérez-Patrigeon S, Ponce De León-Garduño A

Language: Spanish
References: 12
Page: 104-107
PDF size: 553.72 Kb.


ABSTRACT

21-years-old man with untreated HIV infection diagnosed 5 years ago and a history of chronic diarrhea and fever. After the initiation of antiretroviral therapy, he presented acute abdomen. Therefore, a laparotomy was performed and in the anatopathologic examination of resected bowel was observed acid-fast bacilli and intracellular infectious structures of Leishmania. He was treated with Amphotericin B, desoxicolate and anti-tuberculosis treatment. Visceral Leishmaniasis is transmitted by the bite of several sandflies of the genera Phlebotomus and Lutzomyia. It is commonly characterized by fever, chills, vomiting, anemia, hepatosplenomegaly, leukopenia, hypergammaglobulinemia, emaciation, and an earth-gray color of the skin. HIV pandemic has changed the natural history of Leishmaniasis, increasing the risk of visceral Leishmaniasis, with an incidence of 1/100-1000 patients in endemic areas. In HIV patients, Leishmania accelerates the AIDS onset, because of the immunosuppression and the stimulation for the virus replication. According to the World Health Organization (WHO), not a case of Visceral Leishmaniasis coinfection and HIV has been reported in Mexico.


REFERENCES

  1. Report of the Fifth Consultative Meeting on Leishmania/HIV Coinfection. Addis Ababa, Ethiopia, 20–22 March 2007. WHO/2007.5.

  2. Alvar J, Cañavate C, B Gutiérrez-Solar, M Jiménez, F Laguna, R López Vélez, et. al. Leishmania and Human Immunodeficiency Virus Coinfection: the First 10 Years. Clin Microbiol Rev 1997;298-319.

  3. Jheman Zetina JL. Leishmaniasis cutánea en el estado de Quintana Roo, México. Dermatología Rev Mex 2008; 52.

  4. Monroy A, Sanchez-Tejeda G. Molecular probes and the polymerase chain reaction for detection and typing of Leishmania species in Mexico. Trans R Soc Trop Med Hyg 2002;96: s101-s104.

  5. Alvar J, Aparicio P, Aseffa A, Den Boer M, Cañavate C, Dedet JP, et al. The relationship between Leishmaniasis and AIDS: the Second 10 Years. Clin Microbiol Rev 2008; 21:2.

  6. Pascual I, Monasterio P, et al. Abdomen agudo en paciente VIH por Leishmaniasis visceral. Rev Esp Enferm Dig 2007; 99:49-60.

  7. Pérez C, Solías Y, Rodríguez G. Leishmaniasis cutánea difusa en un paciente con SIDA. Biomédica 2006; 26: 485-497.

  8. Alexandrino P, Santos J, Dorval ME, Da-Costa FC, Pereira GR, da Cunha RV, et al. HIV/AIDS-associated visceral Leishmaniasis in patients from an endemic area in Central-west Brazil. Mem Inst Oswaldo Cruz, Rio de Janeiro 2010; 105:692-697.

  9. Wang J, Vanley C, Miyamoto E, Turner J, Peng S. Coinfection of Visceral Leishmaniasis and Mycobacterium in a Patient with Acquired Immunodeficiency Syndrome. Arch Pathol Lab Med 1999; 123:835-837.

  10. Chappuis F, Sundar S, Hailu A, Ghalib H, Rijal S, W. Peeling R, et al.Visceral Leishmaniasis: What are the needs for diagnosis, treatment and control?. Nat Rev Microbiol 2007; 5.

  11. Mondal S, Bhattacharya P, Ali N. Current diagnosis and treatment of visceral Leishmaniasis. Expert Rev Anti Infect Ther 2010; 8:919-944.

  12. Ter Horst R, Collin S.M., Ritmijer K, Bogale A, Davidson RN. Concordant HIV infection and visceral leishmaniasis in Ethiopia the influence of antirretroviral treatment and other factores on outcome. ClD 2008; 46(11):1702-9.




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