Figueroa CI, Saavedra MD, de la Torres SY, Sánchez LM

Language: Spanish
References: 16
Page:
PDF size: 61.60 Kb.

ABSTRACT

Introduction: congenital malformations significantly increase infant mortality rates and jeopardize the quality of infant life.
Objective: to quantify the genetic-caused interruptions and to know the most common birth defects in the population.
Methods: a descriptive study was conducted in Ana Betancourt de Mora Provincial Teaching Hospital, in Camaguey, from January 1st 2004 to December 31st 2011. 511 pregnant women were the universe and the sample of this study. These subjects were diagnosed with congenital malformation, and they underwent termination of pregnancy due to genetic causes. The data was gathered from genetic records and a survey was applied for the variables under study.
Results: 46.38 % of these patients were 20-35 years old and 44.51 % stopped pregnancy in 24-26 weeks of pregnancy, with a product weighted £ 500 g (53.23 %) 49.32 % of these products were male.
Conclusions: there were 511 interruptions of pregnancy. 40.50% were due to nervous system malformations and 18.13% due to kidney malformation.

REFERENCES

1. Pérez M, Fuentes LT. Experiencia de Veinte Años del Registro Cubano de Malformaciones Congénitas. Rev Cubana Genet Comunit. 2007;1(2):28-34.

2. Cunningham F, Gant N, Leveno K, Gilstrap L, Hauth J, Wenstrom K. Williams Obstetricia. 21ra. ed. La Habana: Editorial Ciencias Médicas; 2007. p. 801- 888.

3. Scout JR , Di Saia PJ, Hammond ClB, Spellacy Wn, Hauth JC. Danforth. Tratado de Obstetricia y Ginecología. 8va. Ed. México: Mcgraw- Hill Interamericana; 2000. p.181-204.

4. Donoso E, Villaroel L. Edad materna avanzada y riesgo reproductivo. Rev Méd Chile. 2003;131:55-9.

5. Pérez. MT, Fuentes LT. Actitudes de individuos de la población cubana hacia el Aborto Selectivo. Rev Cubana Genet Comunit. 2007;1(2):15-20.

6. Rodrigo C, Canaval H, Prieto C. Obstetricia de alto riesgo. 6ta ed. Colombia: Ed Distribuna; 2007. p. 101- 108.

7. Delgado O, Lantigua A, Cruz G, Díaz C, Bardasquera D. Interrupciones de embarazo por malformaciones congénitas. Rev Cubana Med Gen Integr. 2007;23(2).

8. Nacer H, Cifuentes O, Millan Z, Vacarisas A, Kobrich S. La edad paterna como factor de riesgo para las malformaciones congénitas. Rev Méd Chil. 2008;136(2):201-8.

9. Osorio A, Rodríguez JM. Embriopatías Asociadas al Uso de Misoprostol. Rev Chil Obstet Ginecol. 2007;72(5):346-51.

10. Aguilar S, Castillo D, Oliva J. Aquinesia Fetal. Presentación de dos casos. Congreso Virtual Hipanoamericano de Anatomía Patológica. Mht. No 918. La Habana; 2007.

11. Botto LD, Lisi A, Robert- Gnansia E. International Retrospective Cohort Study of Neural Tube Defect in Relation to Folic Acid Recommendations Working. BMJ. 2005;20(12);571.

12. Ducarme G, Graesslin O, Alanio E. Increased Nuchal Traslucensy and Cistyc Hygroma in the First Trimestrer: Prenatal Diagnosis And Neonatal Outcome. Gynecol Obstet Fertil. 2005;33(10):750-4.

13. Thakur V, Gilbert HL, Akinfenwa O. Case Report of Prenatal Diagnosis of Penta X Synbrome in Association with Insolated Borderline Ventriculomegaly. J Obstet Gynecol. 2005;25(2):208-9.

14. Bailey LB, Berry RJ. Folic Acid Suplementation and the Ocurrence of Congenital Heart Defect, Orofacial Clefts, Multiple Births, and Misscarriage. Am J Clin Nutr. 2005;81(5):1213-7.

15. Ball RH, Caughey AB, Malone FD. First and Second Trimestrer Evaluation of Risk for Down Sindrome. Obstet Gynecol. 2007;110(1):10-7.

16. Ultrasound and Autopsy Findings After 2nd Trimester Terminations of Pregnancy. J Perinatal Med. 2008;36(1):59-69.