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2012, Number 3

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Rev Cubana Invest Bioméd 2012; 31 (3)

Morphogenesis of dentinal tubules: a mathematical model

Niño BJL, Garzón-Alvarado DA

Language: Spanish
References: 39
Page: 352-362
PDF size: 170.05 Kb.


ABSTRACT

Mesenchymal differentiation into odontoblasts is a complex process determining the formation of dentinal tubules. The process involves a carefully regulated sequence of changes in the behavior of mesenchymal cells, coordinated by the expression of various molecular factors, particularly Noggin and BMP2. In this paper the formation of dentinal tubules is simulated using a reaction-diffusion mathematical model solved by the finite element method.


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