Niño BJL, Garzón-Alvarado DA

Idioma: Español
Referencias bibliográficas: 39
Paginas: 352-362
Archivo PDF: 170.05 Kb.

RESUMEN

La diferenciación mesenquimal a odontoblasto es un proceso complejo que determina la formación de los túbulos dentinales. Este proceso involucra una cuidadosa y regulada secuencia de cambios en el comportamiento de las células mesenquimales, coordinados por la expresión de diferentes factores moleculares, entre ellos, principalmente, el Noggin y BMP2. En este artículo se simula la formación de los túbulos dentinales a partir de un modelo matemático de reacción difusión que es solucionado por el método de los elementos finitos.

REFERENCIAS (EN ESTE ARTÍCULO)

1. Lesot H, Lisi S, Peterkova R, Peterka M, Mitolo V, Ruch JV. Epigenetic signals during odontoblast differentiation. Adv Dent Res. 2001 Aug;15:8-13.

2. Mina M, Kollar EJ. The induction of odontogenesis in non-dental mesenchyme combined with early murine mandibular arch epithelium. Arch Oral Biol. 1987;32(2):123-7.

3. Ruch JV, Lesot H, Begue-Kirn C. Odontoblast differentiation. Int J Dev Biol. 1995 Feb;39(1):51-68.

4. Thesleff I. Tooth morphogenesis. Adv Dent Res. 1995 Nov;9(3 Suppl):12.

5. Thesleff I. Homeobox genes and growth factors in regulation of craniofacial and tooth morphogenesis. Acta Odontol Scand. 1995 Jun;53(3):129-34.

6. Aberg T, Wozney J, Thesleff I. Expression patterns of bone morphogenetic proteins (Bmps) in the developing mouse tooth suggest roles in morphogenesis and cell differentiation. Dev Dyn. 1997 Dec;210(4):383-96.

7. Kettunen P, Laurikkala J, Itaranta P, Vainio S, Itoh N, Thesleff I. Associations of FGF-3 and FGF-10 with signaling networks regulating tooth morphogenesis. Dev Dyn. 2000 Nov;219(3):322-32.

8. Kettunen P, Thesleff I. Expression and function of FGFs-4, -8, and -9 suggest functional redundancy and repetitive use as epithelial signals during tooth morphogenesis. Dev Dyn. 1998 Mar;211(3):256-68.

9. Thesleff I, Mikkola M. The role of growth factors in tooth development. Int Rev Cytol. 2002;217:93-135.

10. Thesleff I. Epithelial-mesenchymal signalling regulating tooth morphogenesis. J Cell Sci. 2003 May 1;116(Pt 9):1647-8.

11. Thesleff I, Vaahtokari A, Vainio S, Jowett A. Molecular mechanisms of cell and tissue interactions during early tooth development. Anat Rec. 1996 Jun;245(2):151-61.

12. Mammoto T, Mammoto A, Torisawa YS, Tat T, Gibbs A, Derda R, et al. Mechanochemical control of mesenchymal condensation and embryonic tooth organ formation. Dev Cell. Oct 18;21(4):758-69.

13. Arana-Chavez VE, Massa LF. Odontoblasts: the cells forming and maintaining dentine. Int J Biochem Cell Biol. 2004 Aug;36(8):1367-73.

14. Mitsiadis TA, Graf D. Cell fate determination during tooth development and regeneration. Birth Defects Res C Embryo Today. 2009 Sep;87(3):199-211.

15. Lisi S, Peterkova R, Peterka M, Vonesch JL, Ruch JV, Lesot H. Tooth morphogenesis and pattern of odontoblast differentiation. Connect Tissue Res. 2003;44 Suppl 1:167-70.

16. Ferrario VF, Sforza C, Colombo A, Carvajal R, Duncan V, Palomino H. Dental arch size in healthy human permanent dentitions: ethnic differences as assessed by discriminant analysis. Int J Adult Orthodon Orthognath Surg. 1999;14(2):153-62.

17. Kumasaka S, Shimozuma M, Kawamoto T, Mishima K, Tokuyama R, Kamiya Y, et al. Possible involvement of melatonin in tooth development: expression of melatonin 1a receptor in human and mouse tooth germs. Histochem Cell Biol. May;133(5):577-84.

18. Nanci A. Oral Histology. 7th ed.: Filadelfia, USA:Elsevier Inc.; 2008.

19. Bartold Mark, Narayanan S. Biology of the periodontal connective tissues. Exeter, UK:Quintessence Publishing; 1998.

20. Carda C, Peydro A. Ultrastructural patterns of human dentinal tubules, odontoblasts processes and nerve fibres. Tissue Cell. 2006 Apr;38(2):141-50.

21. Linde A. Dentin mineralization and the role of odontoblasts in calcium transport. Connect Tissue Res. 1995;33(1-3):163-70.

22. Wakabayashi H, Matsumoto K, Nakamura Y, Shirasuka T. Morphology of the root canal wall and arrangement of underlying dentinal tubules. Int Endod J. 1993 May;26(3):153-8.

23. Tompkins K. Molecular mechanisms of cytodifferentiation in mammalian tooth development. Connect Tissue Res. 2006;47(3):111-8.

24. Vainio S, Karavanova I, Jowett A, Thesleff I. Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development. Cell. 1993 Oct 8;75(1):45-58.

25. Yang W, Harris MA, Cui Y, Mishina Y, Harris SE, Gluhak-Heinrich J. Bmp2 is required for odontoblast differentiation and pulp vasculogenesis. J Dent Res. Jan;91(1):58-64.

26. Schmitt R, Ruch JV. In vitro synchronization of embryonic mouse incisor preodontoblasts and preameloblasts: repercussions on terminal differentiation. Eur J Oral Sci. 2000 Aug;108(4):311-9.

27. Tziafas D, Kodonas K. Differentiation potential of dental papilla, dental pulp, and apical papilla progenitor cells. J Endod. May;36(5):781-9.

28. Butler WT. Dentin matrix proteins. Eur J Oral Sci. 1998 Jan;106 Suppl 1:204-10.

29. Begue-Kirn C, Krebsbach PH, Bartlett JD, Butler WT. Dentin sialoprotein, dentin phosphoprotein, enamelysin and ameloblastin: tooth-specific molecules that are distinctively expressed during murine dental differentiation. Eur J Oral Sci. 1998 Oct;106(5):963-70.

30. Linde A. Dentin matrix proteins: composition and possible functions in calcification. Anat Rec. 1989 Jun;224(2):154-66.

31. Zhu W, Kim J, Cheng C, Rawlins BA, Boachie-Adjei O, Crystal RG, et al. Noggin regulation of bone morphogenetic protein (BMP) 2/7 heterodimer activity in vitro. Bone. 2006 Jul;39(1):61-71.

32. Plikus MV, Zeichner-David M, Mayer JA, Reyna J, Bringas P, Thewissen JG, et al. Morphoregulation of teeth: modulating the number, size, shape and differentiation by tuning Bmp activity. Evol Dev. 2005 Sep-Oct;7(5):440-57.

33. Walsh DW, Godson C, Brazil DP, Martin F. Extracellular BMP-antagonist regulation in development and disease: tied up in knots. Trends Cell Biol. May;20(5):244-56.

34. Begue-Kirn C, Smith AJ, Ruch JV, Wozney JM, Purchio A, Hartmann D, et al. Effects of dentin proteins, transforming growth factor beta 1 (TGF beta 1) and bone morphogenetic protein 2 (BMP2) on the differentiation of odontoblast in vitro. Int J Dev Biol. 1992 Dec;36(4):491-503.

35. Garzón-Alvarado DA, Ramírez Martínez AM. A biochemical hypothesis on the formation of fingerprints using a turing patterns approach. Theor Biol Med Model. 2011;8(1):24.

36. Murray JD. Parameter space for turing instability in reaction diffusion mechanisms: a comparison of models. J Theor Biol. 1982 Sep 7;98(1):143-63.

37. Balemans W, Van Hul W. Extracellular regulation of BMP signaling in vertebrates: a cocktail of modulators. Dev Biol. 2002 Oct 15;250(2):231-50.

38. Garzón-Alvarado DA, Martínez AM, Segrera DL. A model of cerebral cortex formation during fetal development using reaction-diffusion-convection equations with Turing space parameters. Comput Methods Programs Biomed. 2011. Dec;104(3):489-97.

39. Courtin B, Perault-Staub AM, Staub JF. Spatio-temporal self-organization of bone mineral metabolism and trabecular structure of primary bone. Acta Biotheor. 1995 Dec;43(4):373-86.