2010, Number 4
Usefulness of tumoral markers in infertile patients with adnexal masses
Santiago MMI, Marín RO, Hinojosa CJC, Vital RVS
Language: Spanish
References: 9
Page: 101-105
PDF size: 68.30 Kb.
ABSTRACT
Background: Adnexal masses are a frequent cause of gynecological consultation. The diagnostic protocols are based on ultrasonography findings and often on the determination of tumor markers, but the utility of these diagnostic tools is not clear.Objective: To evaluate the usefulness of tumor markers in infertile patients with diagnosis of adnexal mass.
Patients and method: We performed a retrospective observational study that included infertile patients with diagnosis of adnexal masses. As part of diagnostic study a pelvic ultrasound and tumor markers determination were done. Description of the data was carried out through measures of central tendency and dispersion. The inferential analysis was performed using Spearman correlation.
Results: We studied 87 patients with an age range of 12 to 39 years. Of them, 73.5% had a diagnostic of infertility, and 5.7% had a family history of ovarian or colon cancer. The CA-125 was above normal limits in 27% of the patients. Ultrasound was inconclusive in 40% of women. Endometrioma was the tumor more frequently found in the surgical evaluation (38%) and in the histopathological report (26%).
Conclusions: We found a non statistically significant correlation between the ultrasound, surgical and histological findings compared with serum concentrations of the different tumor markers studied.
REFERENCES
Myers ER, Bastian LA, Havrilesky LJ, Kulasingam SL, et al. Management of adnexal mass. Evidence Report/Technology Assessment No. 130 (Prepared by the Duke Evidencebased Practice Center under Contract No. 290-02-0025.) AHRQ Publication No. 06-E004. Rockville, MD: Agency for Healthcare Research and Quality. February 2006.