2012, Number 3
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AMC 2012; 16 (3)
Choroidal melanoma: a case presentation
Rodríguez PA; Gallardo RL; Chávez PI; Borrego LX
Language: Spanish
References: 12
Page: 310-317
PDF size: 120.75 Kb.
ABSTRACT
Background: choroidal melanoma is considered the most common malignant tumor in adults. It usually appears between the sixth and seventh decade of life and it is diagnosed by ophthalmoscopy, biomiscroscopy, ultrasound and fluorescein angiography. Choroidal melanoma presentation may be in its nodular or diffuse variant; malignancy depends on the size of tumor, location, extrascleral extension, histological type, among other factors. The cause of death from this disease usually occurs by hepatic metastases.
Objective: to avoid late diagnosis of ocular melanoma.
Case presentation: a 50-year-old-female patient presented with slow decrease of visual acuity in the right eye. The eye test detected the presence of a brown tumor mass occupying the upper hemiretina, which was corroborated with the observation of ocular ultrasound. It was decided to enucleate the eyeball due to its characteristics. Histopathological examination confirmed the presence of a choroidal melanoma of mixed cell type with ciliary body infiltration. Results of physical, hematological and imaging examination were negative, ruling out the presence of metastasis.
REFERENCES
Singh A, Damato B, Murphee A, Perry J. Oncología clínica oftálmica. Madrid: Elsevier Saunders; 2009.
Ríos Torres M, Capote Cabrera A, Hernández Silva R, Eguias Martínez F, Padilla González C. Oftalmología. Criterios y tendencias actuales. La Habana: Editorial Ciencias Médicas; 2009.
Shetlar DJ. Basic and clinical science course.Section 4: ophthalmic pathology and intraocular tumors. San Francisco: American Academy of Ophthalmology; 2008.
Callender GR. Malignant melanotic tumors of the eye: a study of histologic types in 111 cases. Trans Am Acad ophthalmol otolaryngol. 1931; (3):131-42.
Goméz Ulla de Irazazábal F, Suárez de Figueroa M, Nadal Reus J. Casos clínicos en retina y Vitreos. Barcelona: Editorial Glosa; 2010.
American Academy of Ophthalmology. Intraocular Inflamation and Uveitis. USA. 2008-2009. Section 9. Basic and Clinical Science Course. San Francisco: American Academy of Ophthalmology; 2010.
Tschentscher F, Husing T, Holter R. Tumor classification based on gene expression profiling shows that uveal melanomas with and without monosomy 3 represent two distinct entities. Cancer Res. 2003; 23(5):2578-84.
Eguias Martínez F, Rios Torres M, Capote Cabrera A. Manual de tratamiento y diagnóstico en oftalmología. La Habana: Editorial Ciencias Médicas; 2009.
Seregard S. Posterior uveal melanoma. Acta Ophthalmol Scand. 1996; (74):315-29.
Gamel JW, McLean IW. Cuantitative analysis of the Callender classification of uveal melanoma cells. Arch Ophthalmol. 1997; (95):686-91.
Schmitz-Valckenberg S, Fleckenstein M, Scholl HP, Holz FG. Fundus autofluorescence and progression of choroidal melanoma. Surv Ophthalmol. 2009; 54(1):96-117.
Kitchens JW. Retinal Imaging: The Future is Bright with New Technologies. Pearls in Ophthalmology Retinal Imaging. 2009; (11):23-9.