Labrada DA, Domínguez GY, Fernández WR

Language: Spanish
References: 19
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ABSTRACT

Introduction: The ischemic heart disease is a major determinant of perioperative morbility and mortality.
Objective: To compare two techniques of total intravenous anesthesia in patients with coronary risk factors in an elective major surgical procedure.
Material and Methods: A longitudinal, prospective and descriptive research was conducted in 42 ASA III patients in the "General Calixto GArcía" University Hospital from April, 2008 to April, 2010. Two groups were created according to the anesthesia maintenance (1): propofol/fentanyl and (2): propofol/ketamine. Authors studied the changes in glycemia, mean blood pressure, cardiac frequency and CO2 exhalated during the intraoperative period, as well as the recovery times of each of the techniques. Data were summarized using means and standard deviations (SD) for quantitative variables and percentages for qualitative variables. The test of comparison of means of independent samples was used to comparison between both groups.
Results: The intraoperative glycemia and exhalated CO2 values were similar en both groups without significant differences. During induction, the mean blood pressure and the cardiac frequency were significantly lower in the group 1 compared with group 2 which remains practically without variations in the different moments. The total recovery from anesthesia was faster in the group 2.
Conclusion: The total intravenous anesthesia using ketamine/propofol, yield final positive results and without any major complication, being another tool to decrease the perioperative morbility in patients with coronary risk factors.

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