Santiago-Ramírez MÁ, Rosas-Sumano AB

Language: Spanish
References: 11
Page: 7-12
PDF size: 96.68 Kb.

ABSTRACT

Objective: To know the time lapse between birth, diagnosis, and initiation of treatment of congenital hypothyroidism (CH) in suspected cases reported per neonatal screening at the General Hospital “Dr. Aurelio Valdivieso” in Oaxaca.
Material and Methods: From January 1, 2006, to December 31, 2011, we studied 41 cases with CH detected by neonatal screening; we determined the site of origin of each patient and the health clinic where the sample screens were taken. The days that lapsed between the birth, confirmation, and initiation of treatment, and clinical manifestations of HC at the time of diagnosis were recorded.
Results: The mean age at initiation of treatment was 40.17 days. The cases in which treatment was started within 30 days were 13 (31.7%); those in which treatment was initiated between 30 and 60 days were 22 (53.7%) and those who started treatment after 60 days were 6 (14.6%). Patients with clinical manifestations at the time of diagnosis were 39 (95.1%). In one town, Santiago Suchilquitongo, 6 cases (14.6%) were diagnosed.
Conclusions: The difficulty of access to different parts of the State of Oaxaca contributes to delays in sample collection and the reporting of results of neonatal screening. The time lapse between birth and the initiation of treatment is higher than recommended by the technical guideline for the program of congenital hypothyroidism, and increases the risk of neurological damage in patients; hence, strategies must be designed to allow state-level diagnosis within 30 days of life of the patients.

REFERENCES

1. Sánchez-Pérez C., Calzada R, Ruiz L, Altamirano N, Méndez I, Vela-Amielva M, y cols. Hipotiroidismo congénito. Manifestaciones Clínicas en Niños menores de 15 semanas con tamiz neonatal positivo. Rev Mex Pediatr 2006; 73(6); 272-9.

2. Centro Nacional de Equidad de Género y Salud Reproductiva. Tamiz neonatal, Detección, Diagnóstico, Tratamiento y Seguimiento. Lineamiento Técnico. Gobierno Federal. Salud. 2010.

3. Martínez Medina MA, Orozco Cárdenas MB. Hipotiroidismo Congénito: Reporte de un caso diagnosticado por tamiz neonatal. Bol Clin Hosp Infant Edo Son 2008; 25(2): 115-8.

4. Vela M, Gamboa S, Aguirre BE, y cols. Tamiz Neonatal del Hipotiroidismo Congénito en México. Frecuencia en últimos diez años. Acta Pediatr Méx 2000; 21:99-103.

5. Vela-Amieva M, Gamboa-Cardiel S, Pérez-Andrade ME, Ortiz-Cortés J, González-Contreras CR, Ortega-Velázquez V. Epidemiología del Hipotiroidismo Congénito en México. Salud Pública Mex 2004; 46: 141-8.

6. Setian NS. Hypothyroidism in children: diagnosis and treatment J Pediatr (Rio J). 2007;83 (5 Suppl):S209-16.

7. Moreno JC. Fundamentos Moleculares del Hipotiroidismo congénito. Anales de Ped. 2004; 60:36-41.

8. Félix-Acosta JB, Melchor-Hurtado E. Hipotiroidismo Congénito: Resultado del Programa y Prevalencia en la Clínica Hospital Mochis, segundo nivel de atención médica del ISSSTE. Revista de Especialidades Médico Quirúrgicas 2003; 8: 16-20.

9. Rodríguez-León GA. Tamiz Neonatal para Hipotiroidismo Congénito. Salud Tab 2001; 7(3): 444- 6.

10. Norma oficial mexicana NOM 007-SSA- 1993. Atención a la mujer durante el embarazo, parto y puerperio y del recién nacido: criterios y procedimientos para la prestación del servicio. DOF, tomo CDXCDI, No. 5, México DF, 6 enero 1995.

11. Vela-Amieva M, Ibarra-González I, Rodríguez-León GA, Chablé-Cupil G, Ávila-Guzmán C, Evaristo-López M, Maldonado-Solís MA, Maldonado-Solís F. Optimización del tiempo de diagnóstico del hipotiroidismo congénito en el Estado de Tabasco, México. Salud en Tabasco 2009; 15: 823-7.