Baltazar TJÁ, Sánchez HLA, Cañas PNR

Language: Spanish
References: 25
Page: 68-74
PDF size: 82.09 Kb.

ABSTRACT

Objective: To identify the association between dysglycemia and mortality in critically ill patients.
Patients and methods: We studied a prospective cohort of patients admitted to the Intensive Care Unit (ICU) with normoglycemia. We excluded those with acute complications of diabetes. We recorded demographic and clinical variables and blood glucose was measured daily during the ICU stay. Were classified the patients as normoglycemic (blood glucose › 70 and ‹ 140 mg/dL) and dysglycemics (hyperglycemic, glucose › 140 mg/dL or hypoglycemic, blood glucose ‹ 70 mg/dL). The association between dysglycemia and mortality was analyzed by uni and multivariate logistic regression analysis. A p value ‹ 0.05 was considered statistically significant.
Results: We analyzed 45 patients with mean age of 43.24 years, 60% women. The mean SOFA score was 7.31 and APACHE II score was 15.29. The mean ICU length of stay was 7.4 days and mortality 22.2%. Of these patients, 44.4% developed hyperglycemia and 13.3% hypoglycemia. Dysglycemic patients had significantly higher APACHE II score (17.73 vs 11.95, p ‹ 0.05), more days of mechanical ventilation (8.31 vs 4, p ‹ 0.05), more days of ICU stay (9.58 vs 4.42, p ‹ 0.05) and higher mortality (30.8 vs 10.5%, p ‹ 0.05) than normoglycemic patients. The multivariate analysis did not identified independent risk factors of mortality.
Conclusions: Dysglycemia is not a risk factor for mortality in critically ill patients.

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