2012, Number 1
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Rev Mex Anest 2012; 35 (1)
Dexmedetomidine in orthognathic surgery
Oriol-López SA, Hernández-Bernal CE
Language: Spanish
References: 30
Page: 46-52
PDF size: 110.73 Kb.
ABSTRACT
Orthognathic surgery, is widely used in the world, because correct dentofacial disharmonies, these are very precise procedures. Intraoperative bleeding, which occurs in these surgeries, is important, therefore, the chances are for a blood transfusion. Decrease bleeding, is a goal in the anesthetic management. The agonist α
2, as the dexmedetomidine, reduce the requirements of other drugs employed both in the induction as the anesthetic maintenance, action which is apparently related to the inhibitory effect on the central transmission of type antidepressant.
Results: We included 55 records of patients, both sexes, undergoing orthognathic surgery, with nasal intubation, maintenance anesthetic with isoflorane or sevoflorane plus dexmedetomidina infusion. Found bradycardia of 12%, mean blood pressure around the 70 mmHg, average consumption of 43.5 mL of isoflorane and 78 mL of sevoflorane, dexmedetomidine 191.64 µg, fentanyl 254.53 µg, bleeding of 478 mL.
Conclusion: The use of adjuvant dexmedetomidine in the anesthetic management is another option, which maintains tension figures suitable, without significant bleeding decreasing transfusion requirement.
REFERENCES
Yu C, Chow T, Kwan A, Wong S, Fung S. Intra-operative blood loss and operating time in orthognathic surgery using induced hypotensive general anaesthesia: prospective study. HKMJ 2000;6:307-311.
Miyawaki T, Kohjitani A, Maeda S, Higuchi H, Shimada M. Effects of isoflurane-induced and prostaglandin E1-induced hypotension on cytokine responses to oral and maxillofacial surgery. J Clin Anesth 2004;16:168-172.
Gong S, Krishnan V, Waack D. Blood transfusions in bimaxillary orthognathic surgery: are they necessary? Int J Adult Orthod Orthognath Surg 2002;17:314-317.
Naval L, González R, Rodríguez CF, Muñoz M, Sastre J. Autotransfusión sanguínea en cirugía ortognática: necesario. Rev Esp Cir Oral y Maxilofac 2006;28:327-331.
Praveen K, Narayanan V, Muthusekhar MR, Baig MF. Hypotensive anaesthesia and blood loss in orthognathic surgery: a clinical study. Br J oral Maxillofac Surg 2001;39:138-140.
Shepherd J. Hypotensive anaesthesia and blood loss in orthognathic surgery. Evid Based Dent 2004;5:16.
Toranzo FJ, Metlich MM, Gutiérrez LC, Rojas LL. Consideraciones anestésicas en cirugía maxilofacial. Rev ADM 2005;62:205-212.
Delgado AV, Sanders JC. A simple technique to reduce epistaxis and nasopharyngeal trauma during nasotracheal intubation in a child with factor IX deficiency having dental restoration. Anesth Analg 2004;99:1056-1057.
Yamaguchi H. Effects of intermaxillary fixation during orthognathic surgery on respiratory function after general anesthesia. Anesth Prog 2001;48:125-129.
Jorden V, Tung A. Dexmedetomidine: clinical update. Seminars in anesthesia, perioperative medicine and pain. Elsevier Science 2002;21:265-274.
Mato M, Pérez A, Otero J, Torres LM. Dexmedetomidina, un fármaco prometedor. Rev Esp Anestesiol Reanim 2002;49:407-420.
Coursin BD, Coursin DB, Maccioli GA. Dexmedetomidine. Curr Opin Crit Care 2001;7:221-226.
Karol MD, Maze M. Pharmacokinetics and interaction pharmacodynamics of dexmedetomidina in humans. Baillière’s Clinical Anaesthesiology 2000; 14:261-269.
Murthy T, Singh R. Alpha 2 adrenoceptor agonist–dexmedetomidina. Role in anaesthesia and intensive care: a clinical review. J Anaesth Clin Pharmacol 2009;25:267-272.
Bathia P. Dexmedetomidine: a new agent in anaesthesia & cirtical care practice. Available in: http://dexmedetomidine.com (acceso 20 febrero 2009).
González M. Analgesia multimodal postoperatoria. Rev Soc Esp Dolor 2005;12:112-118.
Bagatini A, Gomes CR, Zanettini MM, Rezer G. Dexmedetomidina: farmacología e uso clínico. Rev Bras Anestesiol 2002;52:606-617.
Calderón EL, García LM, Meléndez HJ. Tiempos de recuperación y costos en cirugía ambulatoria, utilizando diferentes técnicas anestésicas. Ensayo clínico controlado. Rev Col Anest 2005;33:237-244.
Rodrigo C. Induced hypotension during anesthesia, with special reference to orthognathic surgery. Anesth Prog 1995;42:41-58.
Rodrigo C. Anesthetic considerations for orthognathic surgery with evaluation of difficult intubation and technique for hypotensive anesthesia. Anesth Prog 2000;47:151-156.
Hernández AF, Regalado R, Mair D. Autotransfusión sanguínea en cirugía ortognática: no necesario. Rev Esp Cir Oral y Maxilofac 2006;28:333-338.
Richa F, Yazigi A. Effect of dexmedetomidine on blood pressure and bleeding in maxillo-facial surgery. Eur J Anaesthesiol 2007;24:985-986.
Jacobucci FG, Morales M, Iwaki FL, Payán AJ, Camarín ET, Prevdelli I, Coelho L. Induced hypotension in orthognathic surgery: a comparative study of 2 pharmacological protocols. J Oral & Maxillofacial Sur 2008;66:2261-2269.
Grando TA, Puricelli, Bagatini A, Gomes CR, Guerra BC, Ponzoni D. Alterações pós-anestésicas do hematócrito em cirurgias ortognáticas. Rev Bras Anestesiol 2005;55:78-86.
Weiskopf RB, Eger EI II. Comparing the costs of inhaled anesthetics. Anesthesiology 1993;79:1413-1418.
Rodrigues NR. Cavalcante SL. Influência da dexmedetomidina na concentração expirada do sevoflurano. Avaliação pelo índice bispectral, taxa de supressão e análise espectral da potência do eletroencefalograma. Rev Bras Anestesiol 2002;52:133-145.
Magalhães E, Sousa GC, Araújo LL, Vieira EB. Relação entre a infusão contínua de dexmedetomidina e a fração expirada de sevoflurano monitorizada pelo índice B-bispectral. Rev Bras Anestesiol 2004;54:303-310.
Multz AS. Prolonged dexmedetomidine infusion as an adjunct in treating sedation-induced withdrawal. Anesth Analg 2003;96:1054-1055.
Maccioli GA. Dexmedetomidine to facilitate drug withdrawal. Anesthesiology 2003;98:575-578.
Finkel JC, Elrefai A. The use of dexmedetomidine to facilitate opioid and benzodiazepine detoxification in an infant. Anesth Analg 2004;98:1658-1659.