Guerra N, Cárdenas E, Lester J, Laventman J

Language: Spanish
References: 18
Page: 42-45
PDF size: 314.82 Kb.

ABSTRACT

Creutzfeldt-Jakob disease (CJD) is a neurodegenerative disorder with low incidence, only one case per million in worldwide. The clinical manifestations are varied, ataxia and tremor are the most commonly reported, the visual manifestations include blurred vision, impaired color saturation, visual hallucinations, cortical blindness and optic agnosia are more related to the Heidenhain variant. We describe a woman of 73 years, with sudden visual loss and irritability, in the course of a month develop general cognitive impairment, impaired speech, excessive sleepiness and myoclonic jerks. After considering and discarding differential suspected CJD. The EEG showed abnormal electrical activity with sharp waves and generalized slow-wave spikes, slightly higher areas left and short-wave suppression and triphasic waves are not regular. MR diffusion and FLAIR hyperintense left temporal picture in the cortical region and a smaller pontoencefalic union. Diagnosis was confirmed with positive protein 14-3-3 in CSF.

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