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Órgano de difusión oficial del Instituto Materno Infantil del Estado de México

2011, Number 2

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Arch Inv Mat Inf 2011; 3 (2)

Fisher Evans y lupus eritematoso sistémico

Bobadilla MOPV, Nájera CMF, Mejía LD, Sánchez CJL

Language: Spanish
References: 12
Page: 93-97
PDF size: 70.34 Kb.


ABSTRACT

Described for the first time by Robert Evans in 1951, the syndrome of Evans is an atypical and with a low frequency immunological disease, with an unclear aetiology, mainly in the paediatric age it is characterized by autoimmune haemolytic anemia, and is associated with lymphoproliferatives syndromes, primary immunodeficiencies and systemic erythematous lupus. The syndrome of Evans in children is a heterogenous disease with significant morbidity and mortality, with tendency to chronicity and recurrences. It is characterized by the presence of haemolytic anemia with test of positive direct Coombs and it is associated to autoimmune trombocitopenia with or without mucous hemorrhage and petequias. The present modalities of treatment are palliative than curative. The main treatment of the Evans syndrome is the corticosteroids, nevertheless the intravenous immunoglobuline, splenectomy, azatioprine and the cyclosporin are the other options of treatment.


REFERENCES

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