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2011, Number 2

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Residente 2011; 6 (2)

Dolor neuropático: diagnóstico, mecanismos fisiopatológicos y tratamiento

Barragán IP, Cervantes DC, Quiñonez BGN, Granados SV

Language: Spanish
References: 39
Page: 96-104
PDF size: 74.12 Kb.


ABSTRACT

Neuropathic pain develops as a result of lesions or disease affecting the somatosensory nervous system either in the periphery or centrally. Examples of neuropathic pain include painful polyneuropathy, postherpetic neuralgia, cancer pain, trigeminal neuralgia, and post-stroke pain, among others. Clinically, neuropathic pain is characterised by spontaneous ongoing or shooting pain and evoked amplified pain responses after noxious or non-noxious stimuli. Methods for screening and assessment focus on the presence and quality of neuropathic pain. While, basic research is enabling the identification of different pathophysiological mechanisms. Clinical assessment of symptoms and signs can help to determine which mechanisms are involved in specific neuropathic pain disorders. Management of neuropathic pain requires an interdisciplinary approach, centred around pharmacological treatment. A better understanding of neuropathic pain and, in particular, of the translation of pathophysiological mechanisms into sensory signs will lead to a more effective and specific mechanism-based treatment approach.


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