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2010, Number 4

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Anales de Radiología México 2010; 9 (4)

Posterior fossa tumors in pediatric patients and its correlation to clinical, radiological and anatomopathological

Cano MI, Enriquez CNC

Language: Spanish
References: 44
Page: 185-205
PDF size: 1072.72 Kb.


ABSTRACT

Background: Primary tumors of the central nervous system represent about 2% of total adult malignancies and 20% of all malignancies in children. After the leukemias are the second most common childhood cancer.
Objective: To determine the frequency and radiological correlation with clinicopathological behavior of posterior fossa tumors in children treated at the Hospital San Jose Tec de Monterrey.
Material and methods: descriptive study, carried out based on hospital records of 47 pediatric patients diagnosed with posterior fossa tumors treated at the Hospital San Jose Tec de Monterrey in January 1990 to May 2009. Variables were: age, sex, clinical features, location, extent of tumor and histological type, measures of central tendency, dispersion, position, quantitative variables and the observed frequencies for qualitative variables.
Results: The highest percentage of posterior fossa tumors occurred in the age group of 1 to 5 years (21) and 6 -10 (13), which represented 45 and 28% respectively. The major statistical volume of posterior fossa tumors was astrocytoma (34%), followed by medulloblastoma (21.3%), ependymoma (19.1%), glioma (12.8%), oligodendroglioma (4.3%), ganglioglioma, meningioma, hemangioblastoma, papilloma choroid plexus (2.1%). The initial symptoms experienced by the patients with posterior fossa tumors were headache and vomiting (40.4%) and only vomiting (25.5%). 53.2% of patients had no accompanying symptoms.
Conclusion: Over the years the frequency by sex and age group remains the same, like tumor diagnosis by computed tomography or magnetic resonance imaging with contrast have had the same behavior described in other series.


REFERENCES

  1. Sardiñas N, Marcos R, Pestaña EM y cols. Tumores de Fosa Posterior en el niño. Rev Neurol 1999.; 28 (12):1153-1158.

  2. Robustelli G. Gasparini M. Neoplasias del sistema nervioso. En Bonadonna G. Robustelli G. eds. Manual de Oncologia Médica. La Habana Cientifico- Tecnica. 1986 p. 445-59.

  3. Heideman RC, Pocker RJ, Albright LA, Freeman. CR, Rocke LB. Tumors of the Central Nervous System. In Pizzo PA, Poplack DG. Eds. Principles and practice of pediatric oncology. 2 ed Philadelphia:Lippincott Company; 1993p. 633-4.

  4. Valenzuela R H. Manual de Pediatria. 11ma ed. México D F: Interamericana 1993; 567-69.

  5. Garcia Tigera S, Simon Conton L. Epilepsia en gliomas de los hemisferios cerebrales. Rev Cub Ped 1981: 53; 49-55.

  6. Jennet B. Introducción a la neurocirugla. 11ma ed. Barcelona: Salvat Editores 1984; 133-153.

  7. Phillips MF. Sutton LN. Shunt L. Tumores de fosa posterior en niños. Rev Neurol 1997; 25: 927-241.

  8. Koeller K,K., Rushing E.J, From the Archives of the AFIP : Pilocytic Astrocytoma: Radiologic- Pathologic Correlation RadioGraphics 2004; 24:1693-1708.

  9. Radhakrishnan K, Bohnen NI, Kurland LT. Epidemiology of brain intracranial neoplasm of childhood: a population study. Mayo Clin Proc 1976;51: 51-6.

  10. Burger PC, Scheithauer BW, Paulus W, Szymas J, Giannini C, Kleihues P. Pilocytic astrocytoma. In: Kleihues P, Cavenee W, eds. Pathology and genetics of tumours of the nervous system. Lyon, France: IARC, 2000; 45-51.

  11. Wallner KE, Gonzales MF, Edwards MSB, Wara.WM, Sheline GE. Treatment of juvenile pilocytic astrocytoma. J Neurosurg 1988; 69:171-176.

  12. Levin VA, Leibel SA, Grutin PH, Neoplasms of the Central Nervous System In Devita VT, Hellman S, Rosemberg SA, Eds. Cancer: Principles & practice of oncology. 5 ed. Philadelphia: Lippincott-Ravent Publishers; 1997. pp. 2022-2023.

  13. Pollack IF. Brain tumors in children. N Engl J Med 1994; 331:1500-7

  14. Abdollahzadeh M, Hoffman HJ, Blazer SI, et al. Benign cerebellar astrocytoma in childhood: experience at the Hospital for Sick Children 1980-1992. Childs Nerv Syst 1994; 10:380-383.

  15. Pascual J. Temas de Neurología Pediátrica. La Habana: MINSAP Direccion Nac. Docencia med Sup;1983. P. 267-92.

  16. Pencalet P, Maixner W, Sainte-Rose C, et al. Benign cerebellar astrocytomas in children. J Neurosurg 1999; 90:265-273.

  17. Katsetos CD, Krishna L. Lobar pilocytic astrocytomas of the cerebral hemispheres. I. Diagnosis and nosology. Clin Neuropathol 1994; 13:295- 305.

  18. Lee YY, Van Tassel P, Bruner JM, Moser RP, Share JC. Juvenile pilocytic astrocytomas: CT and MR characteristics. Am J Roentgenol 1989; 152:1263-1270.

  19. Heideman RL, Packer RJ, Albright LA, Freeman CR, Rocke LB. Tumors of the Central Nervous System In Pizzo PA, Poplack DG, eds Principles and practice of pediatric oncology. 2 ed. Philadelphia; Lippincott Company; 1993. P. 633 -634.

  20. Duffner PK Cohen MR, Meyers MH. Survival of children with brain tumors; SEER program 1973-1980. Neurology 1986; 36:597.

  21. Townsend CM, Beauchamp RD, Evers BM, Mattox KL. Sabiston Textbook of Surgery, 17th ed. St. Louis, Mo: WB Saunders; 2004:2164-2166.

  22. Coakley KJ, Huston J 3rd, Scheithauer BW, Forbes G, Kelly PJ. Pilocytic astrocytomas: welldemarcated magnetic resonance appearance despite frequent infiltration histologically. Mayo Clin Proc 1995; 70:747-751.

  23. Geissinger JD, Bucy PC. Astrocytomas of the cerebellum in children. Arch Neurol 1971; 24:125-135.

  24. Mamelak AN, Prados MD, Obana WG, Cogen PH, Edwards MS. Treatment options and prognosis for multicentric juvenile pilocytic astrocytoma. J Neurosurg 1994; 81:24-30.

  25. Austin EJ, Alvord EC Jr. Recurrences of cerebellar astrocytomas: a violation of Collins’ law. J Neurosurg 1988; 68:41-47.

  26. Koeller K.K, Rushing E.J., From the Archives of the AFIP Medulloblastoma: A Comprehensive Review with Radiologic- Pathologic Correlation RadioGraphics 2003; 23:1613-1637.

  27. Celli, P., Scarpinati, M., Nardacci, B.,Cervoni, L., Cantore, G.P.: Gangliogliomas of the cerebral hemispheres. Report of 14 cases with long-term follow-up and review of the literature. Acta Neurochir (Wien) 1993; 125: 52-57.

  28. Hernandez-Pascual, L., Perez-Varela, L.M., Zamora-Garcia, S.: Gangliogliomas intracraneales, a proposito de dos casos. Neurocirugia 1995; 6: 315-318.

  29. Mestre, C., Barcena, A., Canizal, J.M. et al. Ganglioglioma cerebral. A proposito de un caso. Neurocirugia 1994; 5: 47-50.

  30. Nishio, S., Morioka, T., Mihara, F., Gondo, K., Fukui, M.: Cerebral Ganglioglioma with epilepsy: neuroimaging features and treatment. Neurosurg Rev 2001; 24: 14-19.

  31. Haddad, S.F., Moore, S.A., Menezes, A.H., Van Gilder, J.C.: Ganglioglioma: 13 years of experience. Neurosurgery 1992; 13: 171-178.

  32. Ildan, F., Tuna, M., Gocer, I.A., Erman, T., Cetinalp, E.: Intracerebral ganglioglioma: clinical and radiological study of eleven surgically treated cases with followup. Neurosurg Rev 2001; 24: 114-118.

  33. Silver, J.M., Rawlings, Ch.E.,Rossitch, E., Zeidman, S.M., Friedman, A.H.: Ganglioglioma: A clinical study with longterm follow-up. Surg Neurol 1991; 35: 261- 266.

  34. Ulutin, H.C., Onguru, O., Pak, Y.: Postoperative radiotherapy for ganglioglioma; Report of three cases and review of the literature. Minim Invas Neurosurg 2002; 45: 224-227.

  35. Gelabert-González M., Serramito-García R, Arcos-Algaba A., y cols. Gangliogliomas Intracraneales en edad pediátrica. Neurocirugia Contemporanea. Vol 2 Mayo 2005. Pag. 1- 11.

  36. Böhling T, Plate KH, Haltia MJ, et al.: Von Hippel-Lindau disease and capillary haemangioblastoma. In: Kleihues P, Cavenee WK, eds.: Pathology and Genetics of Tumours of the Nervous System. Lyon, France: International Agency for Research on Cancer, 2000, pp 223-6.

  37. Priesemann, M., K. M. Davies, et al. (2006). “Benefits of screening in von Hippel Lindau disease--comparison of morbidity associated with initial tumours in affected parents and children.” Horm Res 66(1): 1-5.

  38. Shuin, T., I. Yamasaki, et al. (2006). “Von hippel-lindau disease: molecular pathological basis, clinical criteria, genetic testing, clinical features of tumors and treatment.” Jpn J Clin Oncol 36(6): 337-43.

  39. Teixidor P., Guillén A.*; Cruz O.** y Costa J.M.* El meningioma en edad pediátrica. Revisión de 10 casos Servicio de Neurocirugía. Hospital de Bellvitge. Barcelona. Servicios de Neurocirugía* y Oncología**. Hospital Sant Juan de Déu. Barcelona.Neurocirugia. 2008: 434-439.

  40. Meningioma, por el Dr. J. Sales Llopis, Servicio de Neurocirugía del Hospital General Universitario de Alicante.

  41. Louis DN, Scheithauer BW, Budka H, von Deimling A, Kepes JJ. Meningiomas. In: Kleihues P, Cavenee WK, eds. Pathology and genetics of tumours of the nervous system: World Health Organisation classification of tumours. Lyon: IARC Press, 2000: 176-84.

  42. Longstreth WT, Dennis LK, McGuire VM, et al. Epidemology of intracranial meningiomas. Cancer 1993; 72: 639-48.

  43. Nakasu S, Hirano A, Shimura T, Llena JF. Incidental meningiomas in autopsy study. Surg Neurol 1987l; 27: 319-22.

  44. Sadetzki S, Flint-Richter P, Ben-Tal T, Nass D. Radiation-induced meningiomas: a descriptive study of 253 cases. J Neurosurg 2002; 97: 1078-82.




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