Rodríguez MH

Language: Spanish
References: 24
Page: 91-101
PDF size: 104.02 Kb.

ABSTRACT

Fresh frozen plasma transfusion has been related with immediate risk with possible patient’s severe consequences. Concentrated the erythrocytes an platelet concentrated may produce graph versus host disease. Fresh frozen plasma is currently employed in: Therapeutic plasma exchange, As a repository of blood coagulation factors in massive transfusion, In case of excessive effect of coumadine anticoagulant, as a source of prothrombinic complex. Blood volume transfusion overload is a serious hazard, particularly in predisposed patients receiving oral anticoagulants. Prothrombin coagulation prolongation time, as isolated factor for plasma transfusion indication is iatrogenic if omission of hemorrhagic clinical evaluation is done. Differential diagnosis of transfusion overload and transfusion related lung injury is mandatory, since it may produce delay in therapeutic measures for a timely relief. Graph versus host disease transfusion related, occurs in predisposed patients as children with immunological deficiency and immunological competent adults. Several clinical cases are transcribed from medical literature which clinical characteristics obligated a differential diagnosis between transfusion related lung injury and transfusion overload. The serious risk consequences of transfusion graft versus host disease are very well illustrated in several cases. So in both syndromes it is mandatory a rigorous clinical evaluation in order to prevent the circulatory overload or to made a timely diagnosis of graft versus host disease.

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