Juárez-Bengoa A, Rodríguez-Perdomo D, Pizano-Zárate ML

Language: Spanish
References: 14
Page: 87-92
PDF size: 142.55 Kb.

ABSTRACT

Objective: To analyze hormonal levels associated with metabolic syndrome in infertile men and to compare metabolic syndrome components, seminal parameters, and hormonal profile in men with and without hypogonadism.
Methods: Sixty infertile men were included in the study. Age, length of time of infertility, weight, body mass index, abdominal circumference, score of 5-item version of International Index of Erectile Function, luteinizing hormone, follicle stimulating hormone, testosterone, estradiol, prolactin, sex hormone-binding globulin, and seminal parameters were compared in patients with and without hypogonadism. Quantitative variables were analyzed with Student´s t test and Mann-Whitney U test was used for variables that did not show normal distribution. Statistical significance was determined when P‹0.05.
Results: Metabolic syndrome prevalence in infertile patients was 61.6%. Testosterone and estradiol were lower in patients with metabolic syndrome and in this group 10.8% presented with hypogonadism. In the group without metabolic syndrome there were no cases of hypogonadism. There was no difference in seminal parameters between groups with and without hypogonadism. In the hypogonadism group weight, body mass index, abdominal circumference and sex hormone-binding globulin were higher and testosterone was lower.
Conclusions: Hypogonadism associated with metabolic syndrome was observed. Given that fertility requires normal hormonal level, metabolic syndrome could be related to hypogonadism genesis and consequently to infertility.

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