2008, Number 3
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Rev Mex Urol 2008; 68 (3)
Five-year experience in the management of superficial transitional cell bladder cancer using BCG in the “Centro Medico Nacional 20 de Noviembre” ISSSTE
Molina-Polo LD, Aragón CM, Casasola GJ, Galicia SR, Castillo HJ
Language: Spanish
References: 17
Page: 160-165
PDF size: 267.34 Kb.
ABSTRACT
Bladder cancer represents the second most frequent tumor of the urinary tract, is more frequent in the white population than in the black and its peak presentation is 65 years of age. The cause of this type of cancer is multifactorial. A total of 90% of all bladder tumors corresponds to transitional cell carcinoma. Intravesical immunotherapy with bacillus Calmette-Guerin (BCG) has been the criterion Standard treatment for superficial carcinoma since 1976.
Materials and Methods. A total of 45 patients from the “20 de Noviembre” National Medical Center of the ISSSTE was evaluated who presented with superficial transitional cell bladder cancer, later managed with transurethral resection of the bladder using BCG and then monitored with control cystoscopy and cytology every 30 days.
Results. The total number of patients studied was 45. Thirty-eight (84%) were men and seven (16%) were women. The instilled doses of BCG oscillated between 81 and 90 mg. A total of 28.88% of all patients studied presented with recurrent tumor at 5 years. Adverse effects from BCG application were classified by group according to frequency: prostatitis, 13 patients (28.8%), epididimitis, 1 patient (2.2%), urinary urgency, 15 patients (33.3%) and hemorrhagic cystitis, 1 patient (2.2%).
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