Chacón RJOJ, Anda GG, Téllez LJ, Solís LÚ

Language: Spanish
References: 15
Page: 24-29
PDF size: 286.91 Kb.

ABSTRACT

Background: A common complication is the uncontrolled hypertension by several factors, managed by the emergency room with oral administration of antihypertensive drugs such as captopril, but one of the drugs with better benefits is magnesium sulphate, as it acts in transport ion modulating calcium channels, the permeability of the cell membrane and neuromuscular excitability, with a hypotensive effect through vasodilation, increased vasorelaxation and blood flow in vascular beds. Objective: To verify that the parenteral administration of magnesium sulphate is better than captopril in the Emergency Department for cases of uncontrolled hypertension. Patients and method: During the study patients met predetermined criteria, with an initial mean blood pressure equal to or greater than 110 mmHg, randomly placed in two groups: group A with 50 mg of captopril administration, while group B with administration of 1.5 g of magnesium sulphate by parenteral via. Both groups with blood pressure measurements serially. The mean scores were analyzed by Student’s t technique and ANOVA. Results: The measurements showed no significant differences at any point in time, showing that MgSO₄ administration is as effective as captopril in reducing blood pressure. Conclusions: Magnesium sulphate is an alternative for the management of uncontrolled hypertension in the Emergency Area.

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