2010, Number 4
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Rev Mex Urol 2010; 70 (4)
Nine and twelve specimens from prostate biopsy and their impact on cancer detection: a comparative study
Urdiales-Ortiz A, Camarena-Reynoso H, Cantellano-Orozco M, Morales-Montor J, Pacheco-Gahbler C, Calderón-Ferro F
Language: Spanish
References: 20
Page: 206-210
PDF size: 3323.77 Kb.
ABSTRACT
Objective: To demonstrate whether a higher number of biopsy specimens increases prostate cancer detection.
Methods: A retrospective study including 149 patients from whom 9 prostate biopsy specimens were taken in 2007 and 166 patients from whom 12 prostate biopsy specimens were taken in 2008 was carried out. Cancer detection frequency was compared in both groups and results were correlated with prostate specific antigen, digital rectal examination, prostate specific antigen density, and biopsy series number.
Results: Cancer frequency detection was 16.78% with 9 specimens and increased to 29.52% with 12 specimens (P= 0.009). There was no significant difference in mean age, prostate specific antigen, prostate volume, and prostate specific antigen density between the two groups. There was no significant increase in cancer detection in either group upon carrying out two or more biopsy series (0% in the 9 specimen group and 5% in the 12 specimen group).
Conclusions: Prostate cancer detection frequency increased significantly when there was an increase from 9 to 12 biopsy specimens. The majority of cases were detected in the first biopsy series.
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