1999, Number 4
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Enf Infec Microbiol 1999; 19 (4)
Differential diagnosis between coccidioidomycosis and tuberculosis in children
Hurtado MJA, Cerecer CP, Esquer ZRA
Language: Spanish
References: 21
Page: 181-186
PDF size: 68.90 Kb.
ABSTRACT
Tuberculosis, in any of its clinical presentations, is a very important public health problem in the northwestern region of Mexico, and Baja California is one of the states with the highest incidence of the disease, reporting 600 new cases during the last four years, 50% of them in the city of Tijuana. Nevertheless, there is a risk to abuse of diagnosis of tuberculosis or not to consider other differential diagnosis as coccidiodomycosis by practitioners in this geographic area because of the high frequency of the disease. On the other hand, due to the continuous migration movement in the state, it is very probable that many of the cases of tuberculosis or coccidiodomycosis could be misdiagnosed when seen by doctors in other regions of the country. This problem is particularly dangerous in children under five years old, because this group of age is more susceptible to develop disseminated forms in both diseases. Tijuana has a high prevalence of tuberculosis and coccidioidomycosis in pediatric population (45.6% of children without BCG are reactive to tuberculin skin test and 10% of children are reactive to spherulin test). Because of all of the previously mentioned and the anarchic growth of the city of Tijuana, its poor urbanization, limited accessibility to health services and its constantly migrating population, both tuberculosis and coccidiodomycosis become a true public health problem. Physiopathology, including immunology aspects, for both diseases, as well as some helpful paraclinical elements for differential diagnosis in pediatric patients are reviewed in the present work.
REFERENCES
Einstein HE, Johnson RH. Coccidioidomycosis: New aspects of epidemiology and therapy. Clin Infect Dis 1993;16:349-56.
Cardone, et al. Coccidioidomycosis: the other great imitator. Cutis 1995;56:33-36.
Kirkland TN, Fierer J. Coccidioidomycosis: A reemerging infectious disease. Emerging Infectious Disease 1996;2:192- 8.
Galgiani JN. Coccidioidomycosis: Changes in clinical expression, serological diagnosis and therapeutic options. Clin Infect Dis 1992;14:S100-5.
Galgiani JN. Coccidioidomycosis: A rational disease of national importance. Rethinking approach for control. Ann Intern Med 1999;130:293-9.
Carrada-Bravo T. La coccidioidomicosis en los niños. Bol Med Hosp Infant Mex 1989;46:507-14.
Valenciano-Vega JI, Richardson V, Valenzuela A. Bronchoesophageal fistulas secondary to coccidioidomycosis. Pediatr Infect Dis J 1994;13:159-61.
Stevens DA. Coccidioidomycosis. N Engl J Med 1995;286:1077- 82.
Laniado-Laborin R, Cárdenas-Moreno R, Alvarez-Cerro M. Tijuana: Zona endémica de infección por Coccidioides immitis. Salud Pub Mex 1991;33:235-9.
Laniado-Laborin R, Cabrales N, López G. Prevalencia de infección tuberculosa en escolares de la ciudad de Tijuana, México. Salud Pub Mex 1998;40:47-52.
Albernathy RS. Tuberculosis: An update. Pediatrics in Review 1997;18:50-58.
Smith S, Jacobs RF, Wilson CB. Immunobiology of childhood tuberculosis: A window on the ontogeny of cellular immunity. J Pediatr 1997;131:16-27.
Bellamy R, Hill AVS. Genetic susceptibility to mycobacteria and other infectious pathogens in humans. Current Opinion in Immunology 1998;10:483-7.
Khan EA, Starke JR. Diagnosis of tuberculosis in children: Increased need for better methods. EID 1998;1(4).
Jacobs RF, Eisench KD. Childhood tuberculosis. Adv Pediatr Infect Dis 1993;8:23-51.
Tuberculosis in children. Bull Int Union Tuberc Lung Dis 1991;66.
Nemir RL, O´Hare D. Tuberculosis in children 10 years of age and younger: three decades of experience during the chemotherapeutic era. Pediatrics 1991;88:236-41.
Ibekwe AO, Shareef ZA, Kindy SA. Diagnostic problems of tuberculous cervical adenitis (scrofula). Am J Otolaryngol 1997;18:202-5.
Libke RD, Granoff DM. Coccidioidomycosis. In: Feigin RD, Cherry JD, editors. Textbook Pediatric Infectious Diseases. 3ª ed. USA, 1992:1916-25.
Nava M, Sweet-Cordero A, Richardson V, Santos JI. Tuberculosis en pediatría: nuevos retos ante un viejo problema. En: Santos JI. Temas de pediatría, infectología, México: Interamericana Mc Graw-Hill, 1996:27-53.
Santos JI, Sweet-Cordero A. Diagnóstico molecular de las enfermedades infecciosas. En: Jiménez E, editor. Temas de pediatría, biología molecular en el diagnóstico clínico. México: Interamericana Mc Graw-Hill, 1998:73-91.