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Patología Revista Latinoamericana

2009, Number 4

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Patol Rev Latinoam 2009; 47 (4)

Astrocytic neoplasms in children: cases of the University Hospital Dr. Jose E Gonzalez

Alvarado BYL, Fuentes RRA, García RG, Morales CC, Ancer AA, Barboza QO, Ancer RJ, Miranda MIC

Language: Spanish
References: 15
Page: 327-330
PDF size: 89.06 Kb.


ABSTRACT

Background: The astrocytic neoplasms are the most frequent primary tumors of the central nervous system (CNS) in children. They are classified according to their histology and grade of the malignancy since they are considered an entity with different biological behavior that requires multidisciplinary treatment. We carried out a study to know the frecuency of these tumors in our population.
Material and method: We studied 56 astrocytic neoplasms in children cared for at the Dr. Jose E. González University Hospital of the UANL from January 1990 to July 2008, diagnosing these according to the WHO Classification of Tumors of the Nervous System 2000. Groups were analyzed by age, sex and location.
Results: Astrocytic neoplasms represent 41.7% of the CNS tumors in our hospital. According to histologic grade, 27 were grade II astrocytomas, 15 grade I astrocytomas, 10 grade IV astrocytomas, and 4 grade III astrocytomas. Of these, 54 (96.4%) were intracranial neoplasms and 2 (3.5%) were located in the spinal cord. With regard to gender 35 (62.5%) patients were male and 21 (37.5%) were female. One case occurred in a child less than 1 (1.7%) year of age, 13 (23.2%) cases ocurred in children between 1 and 5 years, 23 (41%) cases in children between 6 and 10 years and 19 (33.9%) cases in children over 10 years.
Conclusions: Intracranial astrocytic neoplasms predominated, with the most frequent location being the posterior cranial fossa. The most frequent histologic variety was grade II astrocytoma. The disease was predominant in boys and in the 6 to 10 year age group.


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