Martínez GJJ, Lam CZL, León SN

Language: Spanish
References: 16
Page: 46-50
PDF size: 176.25 Kb.

ABSTRACT

Introduction: Children with cancer or hematologic diseases course with a prolonged state of immunosuppression, for that; they present a high susceptibility to acquire nosocomial infections (NI). NI increase the length of hospitalization and morbid-mortality in these patients.
Objective: The aim of this study was to determine the risk factors associated with NI, in children with cancer or hematological malignancy, hospitalized in the Pediatric Hospital of the Sinaloa State.
Method: A retrospective and longitudinal study was conducted in the period January 2007 to December 2007. We reviewed a sample of 271 files with clinical criteria and cultures of NI, and without nosocomial infection; they were the groups case and control, respectively. Multiple logistic regression analysis (MLR) was performed in order to establish risk factors.
Results: The samples were 136 cases and 135 controls, variables or independent factors statistically significant (p ‹ 0.05) in the final analysis of LMR adjusted by age were ≥ 7 days of hospitalization (adjusted Odds Ratio (aOR) = 215.4, 95% confidence interval (CI) = 53.6 - 864), severe neutropenia (aOR = 2.49, 95% CI = 1.62-3.83).
Conclusions: The results suggest the need to take stricter measures and identify patients at early stage or in high-risk of NI children with hematological diseases or cancer affected.

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