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Instituto Nacional de Neurología y Neurocirugía

2008, Number 1

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Arch Neurocien 2008; 13 (1)

Cavernous malformations treated with linac-based radiosurgery at the INNN: preliminary results regarding volumetric response

Moreno-Jiménez S, Reyes-Moreno I, Axayacalt-Gutiérrez AG, Lárraga-Gutiérrez JM, Suárez-Campos JJ, González-Valdez CK, Zorro-Guio O, García-Garduño OA, Hernández-Bojórquez M, Ballesteros-Zebadúa P, Celis MA

Language: Spanish
References: 28
Page: 8-12
PDF size: 78.34 Kb.


ABSTRACT

Patients with intracranial cavernous malformations normally present with neurological deficit after hemorrhage or with symptomatic epilepsy. Treatment may be expectant, microsurgical resection or radiosurgery. There are still controversies regarding the protection against rebleeding after radiosurgery. In general, everybody agree with the fact of higher complications rates presenting in patients with cavernous malformations treated with radiosurgery in comparison with patients with arteriovenous malformations (AVM’s) with lesions in similar locations and similar sizes and the authors report the outcomes in terms of hemorrhage protection and seizure control. Reports analyzing changes in lesion volume before and after radiosurgical treatment are lacking. The objective of this study is to show the preliminary results of patients with intracranial cavernous malformations treated with LINAC-based Radiosurgery at the Nacional Institute of Neurology and Neurosurgery in Mexico City, with special emphasis in volumetric analysis.


REFERENCES

  1. Nozipo MJ, Awad IA. Intracranial cavernous malformations: lesion behavior and management strategies. Neurosurgery 1995; 37:591-605.

  2. Raychaudhuri R, Batjer H, Awad I. Intracranial cavernous angioma: a practical review of clinical and biological aspects. Sur Neurol 2005; 63:319-28.

  3. Conway JE, Rigamonti D. Cavernous malformations: a review and current controversias. Neurosurgery Quarterly 2006; 16:15-23.

  4. Hasegawa T, Mclnerney J, Kondziolka D, Lee JYK, Flickinger JC, Lunsford D. Long-term Results after stereotactic radiosurgery with cavernous malformations. Neurosurgery 2002; 50:1190-8.

  5. Chang S, Levy RP, Dler JR, Martin DP, Krakovitz PR, Steinberg GK. Stereotactic radiosurgery of angiographically occult vascular malformations: 14-year experience. Neurosurgery1998; 43;213-20.

  6. Huang YC, Tseng CK, Chang CN, Wei KC, Liao CC, Hsu PW. LINAC radiosurgery for intracranial cavernous malformation: 10-year experience. Clin Neurol Neurosurg 2006; 108:750-6.

  7. Amin-Hanjani S, Ogilvy ChS, Candia GJ, Lyons S, Chapman PH. Stereotactic radiosurgery for cavernous malformations: Klellberg´s experience with proton beam therapy in 98 cases at the Harvard cyclotron. Neurosurgery 1998; 42:1229-36.

  8. Gerwitz RJ, Steinberg GK, Crowley R, Levy RP. Pathological changes in surgically resected angiographically occult vascular malformations after radiation. Neurosurgery 1998; 42:738-42.

  9. O´Connor MM, Mayberg MR. Effects of radiation on cerebral vasculature: a review. Neurosurgery 2000;46:138-51.

  10. Altschuler E, Lunsford LD, Kondziolka D, Wu A, Maitz AH, Schlabassi R, et al. Radiobiologic models for radiosurgery. Neurosurg Clin North Am 1992; 3:61-77.

  11. Alexander E III, Loeffler JS. Radiosurgery for intracranial vascular malformations: techniques, results, and complications. Clin Neurosurg 1992; 39:273-91.

  12. Kida Y, Kobayashi T, Tanaka T. Treatment of symptomatic AOVMs with radiosurgery. Acta Neurochir Suppl (Wien) 1995;63:68-72.

  13. Kondziolka D, Lunsford LD, Flickinger JC, Kestle JR. Reduction of hemorrhage risk after stereotactic radiosurgery for cavernous malformations. J Neurosurg 1995; 83:825-31.

  14. Requena I, Arias M, Lopez-Ibor L, Pereiro I, Barba A, Alonso A, Monton E. Cavernomas of the central nervous system: Clinical and neuroimaging manifestations in 47 patients. J Neurol Neurosurg Psychiatry 1991; 54:590-4.

  15. Seo Y, Fukuoka S, Takanashi M, Nakagawara J, Suematsu K, Nakamura J, Nagashima K. Gamma Knife surgery for angiographically occult vascular malformations. Stereotact Funct Neurosurg 1995; 64:1:98-109.

  16. Stea RA, Schicker L, King GA, Winfield JA. Stereotactic linear radiosurgery for cavernous angiomas. Stereotact Funct Neurosurg 1994; 63:255-65.

  17. Steinberg GK, Levy RP, Fabrikant JI, Frankel KA, Phillips MH, Marks MP. Stereotactic helium ion Bragg peak radiosurgery for angiographically occult intracranial vascular malformations. Stereotact Funct Neurosurg 1991; 57:64-71.

  18. Porter RW, Detwiler PW, Spetzler RF. Pathological changes in surgically resected angiographically occult vascular malformations alter radiation. Neurosurgery 1998; 42:743.

  19. Rigamonti D, Drayer BP, Jonson PC, Hadley MN, Zabramski J, Spetzler RF. The MRI appearance of cavernous malformations (angiomas). J Neurosurg 1987; 67:518-24.

  20. Barker FG, Amin-Hanjani S, Butler WE, Lyons S, Ogilvy ChS, Loeffler JS, Chapman PH. Complication rates alter radiosurgery for cavernous malformations. Neurosurgery 1998; 43:670.

  21. Barker II FG, Amin-Hanjani S, Butler WE, Lyons S, Ojemann RG, Chapman PH, Ogilvy ChS. Temporal clustering of hemorrhages from untreated cavernous malformations of the central nervous system. Neurosurgery 2001; 49:15-25.

  22. Regis J, Bartolomei F, Kida Y, Kobayashi T, Vladyka V, Liscak R, Forster D, Kemeny A, Schrottner O, Pendl G. Radiosurgery for epilepsy associated with cavernous malformation: retrospective study in 49 patients. Neurosurgery 2000; 47:1091-7.

  23. García-Muñoz L, Velasco-Campos F, Lujan-Castilla P, Enriquez-Barrera M, Cervantes-Martínez A, Carrillo-Ruiz J. Radiosurgery in the treatment of brain cavernomas. Experience with 17 lesions treated in 15 patients. Neurochirurgie 2007; 53:243-50.

  24. Kim DG, Choe WJ, Paek SH, Cheng HT, Kim IH, Han DH. Radiosurgery of intracranial cavernous malformations. Acta Neurochir (Wien) 2002; 144:869-78.

  25. Liscak R, Vladyka V, Simonova G, Vymazal J, Novotny J Jr. Gama knife surgery of brain cavernous hemangiomas. J Neurosurg 2005; 102:207-13.

  26. Huang YC, Tseng CK, Chang CN, Wei KC, Liao CC, Hsu PW. LINAC radiosurgery for intracranial cavernous malformation: 10-year experience. Clin Neurol Neurosurg 2006; 108:750-6.

  27. Clatterbuck RE, Moriarty JL, Elmaci I, Lee RR, Breiter SN, Rigamonti D. Dynamic nature of cavernous malformations: a prospective magnetic resonance imaging study with volumetric analysis. J Neurosurg 2000; 93:981-6.

  28. Sure U, Freman S, Bozinov O, Benes L, Siegel AM, Bertalanfy H. Biological activity of adult cavernous malformations: a study of 56 patients. J Neurosurg 2005; 102:342-7.




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