2002, Number 4
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Rev Med Inst Mex Seguro Soc 2002; 40 (4)
Type 2 Diabetes Mellitus Control. Hyperglucose Index As Indicator
Gómez LV, Zúñiga GS, García LE, Couttolenc LMI
Language: Spanish
References: 20
Page: 281-284
PDF size: 104.39 Kb.
ABSTRACT
Objective: To determine whether high glucose index is an alternative and reliable diagnostic method to evaluate control of patients type 2 with diabetes mellitus.
Material and methods: We carried out a transversal, prospective, and comparative study in 90 persons with type 2 diabetes mellitus in which HbAlc was determined. Based on these results, patients were divided into two groups; one group was constituted of patients with HbAlc of ≥ 8 %; this group was identified as patients without control of glucose and the other group whose totals were below this value was considered patients with glucose control. Afterward, high glucose index was calculated in both groups, obtained dividing total glucose on an empty stomach equal to or more than 140 mg/dL by total glucose during the last 3 months. When high glucose index resulted 0.5 or more, we considered that the patient did not have glucose control. A contingency table of 2 x 2 was used to evaluate validity of high glucose index. Sensitivity, specificity and positive and negative values were determined. Confidence intervals of 95% (IC 95 %) were calculated to determine sensitivity and specific reliability.
Results: 70 % of studied patients showed HbAlc totals without glucose control, which corresponds to the epidemiologic reality of this disease. We obtained a sensitivity of high glucose index of 60.3 % (IC 95 % = 50.2 to 69.8 %), a specificity of 77 % (IC 95 % = 69.2 % to 84.8 %), a positive value of 86.4, and a negative value of 45.6 %. Accuracy was 65.5%.
Conclusions: High glucose index (HGI) does not constitute a useful parameter to value glucose control in diabetic patients because it shows a high rate of false negatives.
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