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2010, Number 1

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Cir Cir 2010; 78 (1)

Tumor fibroso solitario gigante de la pleura

Pinedo-Onofre JA, Robles-Pérez E, Peña-Mirabal ES, Hernández-Carrillo JA, Téllez-Becerra JL

Language: Spanish
References: 72
Page: 31-43
PDF size: 396.56 Kb.


ABSTRACT

Background: Fibrous solitary tumor is the second primary malignancy of the pleura and can reach up to 39 cm in diameter; however, to be referred to as “giant” it must occupy at least 40% of the affected hemithorax. Although this tumor usually shows a benign behavior, malignancy criteria have been described. The aim of the study was to assess the initial evaluation, diagnostic procedures, surgical management, treatment outcome, and prognosis.
Methods: We performed a descriptive, observational, longitudinal, and retrospective study from 2002 to 2006 on patients who underwent surgery with a diagnosis of giant solitary fibrous tumor of the pleura.
Results: Six patients were included; 83.3% were females. Mean age was 48 years. All patients were symptomatic, mainly dyspnea, cough and chest pain; 66.7% were leftsided. Preoperative angiography and embolization were performed in 83.3% cases with successful surgical resection. The predominant blood supply was derived from the internal mammalian artery. Intraoperative complication rate was 17%. A vascular pedicle was found in 66.7%. The largest lesion was 40 cm in diameter and weighed 4500 g. Only one case showed high mitotic activity. Mean followup to date is 14 months.
Conclusions: Symptomatology found was consistent with previous reports but in higher percentages. Accurate diagnosis is critical because surgical resection involves a potential cure; however, long-term follow-up is mandatory. Preoperative embolization is recommended due to tumor size.


REFERENCES

  1. Shields TW, Yeldandi AV. Localized fibrous tumors of the pleura. In: Shields TW, LoCicero J, Ponn RB, Rusch VW, eds. General Thoracic Surgery. 6th ed. Philadelphia: Lippincott Williams & Wilkins; 2005. pp. 889-900.

  2. Meziane M. Localized fibrous tumor of the pleura [on line]. Cleveland Clinic Foundation. August 2, 2007. Available at http://www.emedicine.com/radio/topic448.htm

  3. Jha V, Gil J, Teirstein AS. Familial solitary fibrous tumor of the pleura: a case report. Chest 2005;127:1852-1854.

  4. Luckraz H, Ehsan S, Gibbs AR, Butchart EG. A giant pleural fibrous tumor. J Thorac Cardiovasc Surg 2005;130:1216-1217.

  5. Sung SH, Chang JW, Kim J, Lee KS, Han J, Park SI. Solitary fibrous tumors of the pleura: surgical outcome and clinical course. Ann Thorac Surg 2005;79:303-307.

  6. Sánchez-Mora N, Cebollero-Presmanes M, Monroy V, Carretero-Albiñana L, Herranz-Aladro M, Álvarez-Fernández E. Clinicopathological features of solitary fibrous tumors of the pleura: a case series and literature review. Arch Bronconeumol 2006;42:96-99.

  7. Graadt van Roggen JF, Hogendoorn PCW. Solitary fibrous tumor: the emerging clinicopathologic spectrum of an entity and its differential diagnosis. Curr Diagn Pathol 2004;10:229-235.

  8. Briselli M, Mark EJ, Dickersin GR. Solitary fibrous tumors of the pleura: eight new cases and review of 360 cases in the literature. Cancer 1981;47:2678-2689.

  9. DeVita VT, Hellman S, Rosenberg SA. Cancer: Principles & Practice of Oncology, 7th ed. Philadelphia: Lippincott Williams & Wilkins; 2005.

  10. Ortega MV, Gualco G, Musto ML, Wins R, Maggiolo J, Ardao G. Tumor fibroso solitario de la pleura. Aspectos clínico-patológicos. Rev Esp Patol 2005;38:21-25.

  11. Weynand B, Nöel H, Goncette L, Noihomme P, Collard P. Solitary fibrous tumor of the pleura. A report of five cases diagnosed by transthoracic cutting needle biopsy. Chest 1997;112:1424-1428.

  12. Balduyck B, Lauwers P, Govaert K, Hendriks J, De Maeseneer M, Van Schil P. Solitary fibrous tumor of the pleura with associated hypoglycemia: Doege-Potter syndrome: a case report. J Thorac Oncol 2006;1:588-590.

  13. England DM, Hochholzer L, McCarthy MJ. Localized benign and malignant fibrous tumors of the pleura. A clinicopathologic review of 223 cases. Am J Surg Pathol 1989;13:640-658.

  14. Kanthan R, Torkian B. Recurrent solitary fibrous tumor of the pleura with malignant transformation. Arch Pathol Lab Med 2004;128:460-462.

  15. Congregado M, Loscertales J, Jiménez-Merchán R, Arroyo-Tristán A, Girón-Arjona JC, Arenas-Linares C. Giant solitary fibrous tumor of the pleura treated by video-assisted surgery: a case report. Arch Bronconeumol 2004;40:183-184.

  16. Cardillo G, Facciolo F, Cavazzana AO, Capece G, Gasparri R, Martelli M. Localized (solitary) fibrous tumors of the pleura: an analysis of 55 patients. Ann Thorac Surg 2000;70:1808-1812.

  17. Sagawa M, Ueda Y, Matsubara F, Sakuma H, Yoshimitsu Y, Aikawa H, et al. Intrapulmonary solitary fibrous tumor diagnosed by immunohistochemical and genetic approaches: report of a case. Surg Today 2007;37:423-425.

  18. De Leval L, Defraigne JO, Hermans G, Dôme F, Boniver J, Herens C. Malignant solitary fibrous tumor of the pleura: report of a case with cytogenetic analysis. Virchows Arch 2003;442:388-392.

  19. Horton ES, Dobin SM, Donner LR. A clonal t(8;12)(p11.2;q24.3) as the sole abnormality in a solitary fibrous tumor of the pleura. Cancer Genet Cytogenet 2007;172:77-79.

  20. Donner LR, Silva MT, Dobin SM. Solitary fibrous tumor of the pleura: a cytogenetic study. Cancer Genet Cytogenet 1999;111:169-171.

  21. de Perrot M, Fischer S, Bründler MA, Sekine Y, Keshavjee S. Solitary fibrous tumors of the pleura. Ann Thorac Surg 2002;74:285-293.

  22. Tastepe I, Alper A, ÖzaydIn HE, Memiş L, Cetin G. A case of multiple synchronous localized fibrous tumor of the pleura. Eur J Cardiothorac Surg 2000;18:491-494.

  23. Galbis-Caravajal JM, Sales-Badia JG, Navarro-Hervas M, Mafe-Madueno JJ, Cordero- Rodríguez P, Rodríguez-Paniagua JM. Localized fibrous tumors of the pleura: clinical and surgical evaluation. Arch Bronconeumol 2004;40:419-421.

  24. Suter M, Gebhard S, Boumghar M, Peloponisios N, Genton CY. Localized fibrous tumours of the pleura: 15 new cases and review of the literature. Eur J Cardiothorac Surg 1998;14:453-459.

  25. Robinson LA. Solitary fibrous tumors of the pleura. Cancer Control 2006;13:264-269.

  26. Hawthorne HR, Frobese AS. Benign fibroma of the pleura; report of case. Dis Chest 1950;17:588-596.

  27. Ochoa-Ramírez E, Sánchez-Sigel D. Tumores gigantes del tórax: reporte de 3 casos. Avances, Revista de Divulgación Médico Científica, Hospital San José, TEC de Monterrey 2005;3:12-15. Disponible en http://www2.hsj.com.mx/Avances/revista_avances_num_07.pdf

  28. Santolaya CR, Meneses CM, López SJ, Prats MR, Fica DM, González CC, et al. Tumor fibroso solitario de la pleura: análisis de 41 casos. Rev Chil Enf Respir 2007;23:11-16.

  29. Hasan ZA, Molina HR, Tena ML, Mondragón M, Muñoz JG, García F. Tumor fibroso solitario del mediastino. Comunicación de un caso. Med Int Mex 2001;17:101-105.

  30. Alvarado-Cabrero I, Hernández S, Kelly J, Cuenca-Buele S. Tumor fibroso solitario de la pleura. Análisis clínico-patológico de 17 casos. Rev Med Inst Mex Seguro Soc 2006;44:397-402.

  31. McGuire LJ, Chan HS, Pang J. Solitary fibrous tumor of pleura: expression of cytokeratins. Pathology 1990; 22:232-234.

  32. Shiraishi T, Hirayama S, Hiratsuka M, Iwasaki A, Makimoto Y, Iwasaki H, et al. Mediastinal solitary fibrous tumor: report of a case with direct invasion to the trachea. Thorac Cardiovasc Surg 2004;52:110-112.

  33. Breda C, Zuin A, Marulli G, Galligioni A, Rea F. Giant localized fibrous tumours of the pleura: report of three subsequent cases. Lung Cancer 2006;52:249-252.

  34. Chaugle H, Parchment C, Grotte GJ, Keenan DJ. Hypoglycaemia associated with a solitary fibrous tumour of the pleura. Eur J Cardiothorac Surg 1999;15:84-86.

  35. English JC, Leslie KO. Pathology of the pleura. Clin Chest Med 2006; 27:157-180.

  36. Hiraoka K, Morikawa T, Ohbuchi T, Katoh H. Solitary fibrous tumors of the pleura: clinicopathological and immunohistochemical examination. Interact Cardiovasc Thorac Surg 2003;2:61-64.

  37. de Perrot M, Kurt AM, Robert JH, Borisch B, Spiliopoulos A. Clinical behavior of solitary fibrous tumors of the pleura. Ann Thorac Surg 1999;67:1456-1459.

  38. Kohler M, Clarenbach CF, Kestenholz P, Kurrer M, Steiner HC, Russi EW, et al. Diagnosis, treatment and long-term outcome of solitary fibrous tumours of the pleura. Eur J Cardiothorac Surg 2007;32:403-408.

  39. Battifora H, McCaughey WT. Tumors of the serosal membranes. Washington, DC: American Registry of Pathology, Armed Forces Institute of Pathology; 1995. pp. 100–111.

  40. Mahesh B, Clelland C, Ratnatunga C. Recurrent localized fibrous tumor of the pleura. Ann Thorac Surg 2006;82:342-345.

  41. Carretta A, Bandiera A, Melloni G, Ciriaco, Arrigoni G, Rizzo N, et al. Solitary fibrous tumors of the pleura: immunohistochemical analysis and evaluation of prognostic factors after surgical treatment. J Surg Oncol 2006;94:40-44.

  42. Matsumoto H, Wada T, Fukunaga K, Yoshihiro S, Matsuyama H, Nalto K. Bax to Bcl-2 ratio and Ki-67 index are useful predictors of neoadjuvant chemoradiation therapy in bladder cancer. Jpn J Clin Oncol 2004;34:124-130.

  43. Butnor KJ, Burchette JL, Sporn TA, Hammar SP, Roggli VL. The spectrum of Kit (CD117) immunoreactivity in lung and pleural tumors: a study of 96 cases using a single-source antibody with a review of the literature. Arch Pathol Lab Med 2004;128:538-543.

  44. Yokoi T, Tsuzuki T, Yatabe T, Suzuki M, Kurumaya H, Koshikawa T, et al. Solitary fibrous tumour: significance of p53 and CD34 immunoreactivity in its malignant transformation. Histopathology 1998;32:423-432.

  45. MIB-1. In: Veripath OncoDiagnostics [on line]. Southwestern Medical Center. October 15, 2007. Available at

  46. Proliferative index. In: Dictionary of Cancer Terms [on line]. National Cancer Institute. October 15, 2007. Available at http://www.cancer.gov/templates/db_alpha.aspx?CdrID = 44769

  47. Yap CS, Czernin J, Fishbein MC, Cameron RB, Schiepers C, Phelps ME, et al. Evaluation of thoracic tumors with 18F-fluorothymidine and 18F-fluorodeoxyglucose-positron emission tomography. Chest 2006;129:393-401.

  48. Bongiovanni M, Viberti L, Giraudo G, Morino M, Papotti M. Solitary fibrous tumour of the adrenal gland associated with pregnancy. Virchows Arch 2000;437:445-449.

  49. Cakan A, Cagirici U, Yuncu G, Yener AG. Giant benign fibrous tumor of the pleura in a pregnant woman: report of a case. Surg Today 2003;33:196-198.

  50. Sarancone S, Acosta G. Inmunohistoquímica en tumores de partes blandas. En: Jornada 2005 de la Sociedad Argentina de Patología, Buenos Aires, Argentina, 2005. Disponible en http://www.patologia.org.ar/eventos/jornadas/jornada_2005/Curso_1_Lozano/Acosta_Haab-Sarancone/IHQ_Partes_blandas_cor.htm

  51. Maillet M, Fernández-Mateos MP. Citoesqueleto. En: Maillet M, ed. Biología Celular. Madrid: Elsevier-Masson; 2003. pp. 150-151.

  52. Calretinin. In: Nordic Immunohistochemical Quality Control. March 30, 2007. Available at http://www.nordiqc.org/Epitopes/calretinin/calretinin.htm

  53. Bcl-2. In: Cancer Quest [on line]. Emory University. January 17, 2006. Available at http://www.cancerquest.org/index.cfm?page = 571&lang= spanish

  54. Magdeleinat P, Alifano M, Petino A, Le Rochais JP, Dulmet E, Galateau F, et al. Solitary fibrous tumors of the pleura: clinical characteristics, surgical treatment and outcome. Eur J Cardiothorac Surg 2002;21:1087-1093.

  55. Ammar A, El Hammami S, Horchani H, Sellami N, Kilani T. Calcifying fibrous pseudotumor of the pleura: a rare location. Ann Thorac Surg 2003;76:2081-2082.

  56. Kaul P, Kay S, Gaines P, Suvarna SK, Hopkinson DN, Rocco G. Giant pleural fibroma with an abdominal vascular supply mimicking a pulmonary sequestration. Ann Thorac Surg 2003;76:935-937.

  57. Fiorello A, Vicidomini G, Santini M. Giant solitary fibrous tumors of the pleura: two case reports. Thorac Cardiovasc Surg 2007;55:458-459.

  58. Fibla JJ, Gómez G, Salord N, Penagos JC, Estrada G, León C. Giant solitary fibrous tumor of the pleura. Cir Esp 2005;77:290-292.

  59. Adhami N, Ahmed R, Lento PA, Shimshi M, Herman SD, Teirstein AS. Fibrous pleural tumor with hypoglycemia: case study. Mt Sinai J Med 2004;71:344-346.

  60. Sanguinetti CM, Marchesani F, Ranaldi R, Pela R, Cecarini L. Localized fibrous pleural tumour of the interlobular pleural. Eur Respir J 1996;9:1094-1096.

  61. D’Andrilli A, Andreetti C, Ibrahim M, Rendina EA. The evolution of a pleural nodule into a giant fibrous tumor associated with hypoglycemic coma. Eur J Cardiothorac Surg 2007;31:955-957.

  62. Okike N, Bernatz PE, Woolner LB. Localized mesothelioma of the pleura: benign and malignant variants. J Thorac Cardiovasc Surg 1978;75:363-372.

  63. Rena O, Filosso PL, Papalia E, Molinatti M, Di Marzio P, Maggi G, et al. Solitary fibrous tumour of the pleura: surgical treatment. Eur J Cardiothorac Surg 2001;19:185-189.

  64. Desser TS, Stark P. Pictorial essay: solitary fibrous tumor of the pleura. J Thorac Imaging 1998;13:27-35.

  65. Hara M, Kume M, Oshima H, Shibamoto Y, Iida A, Mori Y, et al. F-18 FDG uptake in a malignant localized fibrous tumor of the pleura. J Thorac Imaging 2005;20:118-119.

  66. Cortés J, Rodríguez J, García-Velloso MJ, Rodríguez-Espiteri N, Boan J, Castellano JM, et al. [18F]-FDG PET and localized fibrous mesothelioma. Lung 2003;181:49-54.

  67. Brevetti GR, Sasse KC, Khan JH, Wilson MW, Clary-Macy C, Brevetti LS, et al. Giant tumors of the chest: preoperative embolization and resection. J Cardiovasc Surg 2000;41:945-952.

  68. Ordoñez NG. Localized (solitary) fibrous tumor of the pleura. Adv Anat Pathol 2000;7:327-340.

  69. Weiss B, Horton DA. Preoperative embolization of a massive solitary fibrous tumor of the pleura. Ann Thorac Surg 2002;73:983-985.

  70. Karapolat S, Onen A, Sanli A, Eyuboglu M. Giant solitary fibrous tumor of the pleura. Lung 2008 Mar 21 [Epub ahead of print].

  71. Bini A, Grazia M, Stella F, Petrella F, Bazzocchi R. Giant malignant fibrous histiocytoma of the pleura arising from solitary fibrous tumour. Thorax 2004;59:544.

  72. Nomori H, Horio H, Fuyuno G, Morinaga S. Contacting metastasis of a fibrous tumor of the pleura. Eur J Cardiothorac Surg 1997;12:928-930.




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