2009, Number 2
<< Back Next >>
Rev Endocrinol Nutr 2009; 17 (2)
Visual function modification after treatment with focal photocoagulation of diabetic macular edema
Razo BHDM, Cruz DAS, Lima GV
Language: Spanish
References: 17
Page: 71-75
PDF size: 109.78 Kb.
ABSTRACT
Background: Although some diabetics with macular edema lose vision during the first six weeks after focal photocoagulation, others have no visual changes or improve their visual function. There is the perception that photocoagulation causes visual loss, but the visual modifications that appear during the first weeks of treatment could be attributed to induced inflammation and have not been clearly characterized.
Methods: An observational, descriptive, retrospective, and open study was conducted. Visual capacity measured before and after three weeks of photocoagulation was evaluated in patients with diabetic retinopathy. Patient’s age ranged form 40 to 80, and they were treated at our Ophthalmology Service between January 2006 and December 2007. The proportion and 95% confidence intervals were calculated for visual impairment, significant visual impairment, visual improvement and significant visual improvement.
Results: 79 eyes (56 patients), mean age 60.2 ± 8.4 years 57.1% females. Twenty six eyes had visual impairment after treatment (32.9%, 95% C.I. 22.5-43.3), 32 improved their visual capacity (40.5%, 95% C.I. 29.7-51.3) and 21 did not change their visual function (26.6%, 95% C.I. 16.8-36.4); visual impairment was significant in 7 eyes (8.9%, 95% C.I. 2.6-15.2) and visual improvement in 10 (12.7%, 95% C.I. 5.4-20).
Conclusions: Photocoagulation did not modify visual capacity significantly in most of the treated eyes. The proportion of significant visual impairment was lower than that previously reported at 6 months.
REFERENCES
Fong DS, Aiello LP, Ferris FL, 3rd, Klein R. Diabetic retinopathy. Diabetes Care 2004; 27: 2540-53.
Ryan S, Hinton D, Schachat A, Wilkinson C. Retina. 4th ed. St. Louis: Mosby-Yearbook; 2008.
Klein R, Knudtson MD, Lee KE, Gangnon R, Klein BE. The Wisconsin Epidemiologic Study of Diabetic Retinopathy XXIII: the twenty-five-year incidence of macular edema in persons with type 1 diabetes. Ophthalmology 2009; 116: 497-503.
Fong DS, Aiello L, Gardner TW, King GL, Blankenship G, Cavallerano JD et al. Retinopathy in diabetes. Diabetes Care 2004; 27 (Suppl 1): S84-7.
American Academy of Ophtalmology. Retina and vitreous. In: Ophtalmology AAo. Editor. Basic and clinical science course. San Francisco 2004.
Asociación Mexicana de Retina, Sociedad Mexicana de Oftalmología, Asociación Panamericana de Oftalmología. Resultados del día Panamericano de detección de retinopatía diabética (3 de julio de 1999, día D). Rev Mex Oftalmol 2005; 79: 88-92.
Duanes. Clinical Ophthalmology. Philadelphia Pensilvania 2004.
American Academy of Ophthalmology. Retina Panel. Diabetic Retinopathy. Preferred practice patterns. 2008.
Browning DJ. Interobserver variability in optical coherence tomography for macular edema. Am J Ophthalmol 2004; 137: 1116-7.
Sandhu SS, Birch MK, Griffiths PG, Talks SJ. Short-term effects of focal argon laser treatment in diabetic maculopathy as demonstrated by optical coherence tomography. Retina 2007; 27: 13-20.
American Academy of Ophthalmology. Retina and vitreous. Basic and Clinical Science Course. San Francisco: American Academy of Ophthalmology; 2004.
Early photocoagulation for diabetic retinopathy. ETDRS report number 9. Early Treatment Diabetic Retinopathy Study Research Group. Ophthalmology 1991; 98(5 Suppl): 766-85.
Lima-Gómez V, Rojas-Dosal JA, Domenzain-Afendulis JL. Pérdida visual después de tratamiento con láser en edema macular diabético. Rev Hosp Jua Mex [original]. 2000; 67: 15-20.
Nonaka A, Kiryu J, Tsujikawa A, Yamashiro K, Nishijima K, Kamizuru H, et al. Inflammatory response after scatter laser photocoagulation in nonphotocoagulated retina. Invest Ophthalmol Vis Sci 2002; 43: 1204-9.
Scott IU, Danis RP, Bressler SB, Bressler NM, Browning DJ, Qin H. Effect of Focal/Grid Photocoagulation on Visual Acuity and Retinal Thickening in Eyes with Non Center-Involved Diabetic Macular Edema. Retina 2009.
Lima Gómez V, Olivares-Morales OE, Razo-Blanco-Hernández DM, Hernández-Rojas ML. [Visual deficits at the time of diagnosing clinically significant macular edema in Mexican diabetics]. Salud Pública Mex 2008; 50: 354-5.
Krzystolik MG, Strauber SF, Aiello LP, Beck RW, Berger BB, Bressler NM et al. Reproducibility of macular thickness and volume using Zeiss optical coherence tomography in patients with diabetic macular edema. Ophthalmology 2007; 114: 1520-5.