medigraphic.com

2009, Number 1

<< Back Next >>

Rev Mex Ing Biomed 2009; 30 (1)

Study of tricalcium phosphate cements hydratation

Medina N, Rodríguez H, Piña C

Language: Spanish
References: 33
Page: 54-65
PDF size: 386.75 Kb.


ABSTRACT

The reaction kinetics, the microstructure and transformation mechanism of reagents of three biocementos based on a-tricalcium phosphate (TCP-a), seeds of hydroxyapatite (HA) and zirconium oxide (ZrO2), were studied. It was found that the use of additives enriched with Ca or P, with higher solubility than the solubility of the reactive, it favors the sobresaturation of the liquid phase, which precipitates in CDHA or HA. he CaCl2 and NaH2PO4 act as important sources of Ca2+ and PO43-, it was found that the used concentrations in liquid phase convert com pletely a-TCP in HA in hours, also that the crystallinity is higher employing salts NaH2PO4 than Na2HPO4. They have the advantage over cements of methyl methacrylate, that are usually used, that they react below 40°C while the MMA reach it near to 100°C damaging the surrounding tissue. In addition, these biocements are bioactive and bioabsorbibles. They are proposed for the repair and bone fixation implants and/or prosthetics.


REFERENCES

  1. Jarcho M. Calcium phosphate ceramics as hard tissue prosthetics. Clinical Orthopaedics and Related Research 1981; 157: 259-278.

  2. Higgins TF, Dodds SD, Wolfe SW. A Biomechanical analysis of fixation of intra-articular distal radial fractures with calcium phosphate bone cement. J Bone and Joint Surg 2002; 84: 1579-1586.

  3. Bigi A, Panzavolta S, Rubini K. Setting mechanism of a biomimetic bone cement. Chem Mater 2004; 16(19): 3740-3745.

  4. Ginebra MP, Driessens FCM, Planell JA. Effect of the particle size on the micro and nanostructural features of a calcium phosphate cement: a kinetic analysis. Biomaterials 2004; 25: 3453-3462.

  5. Ginebra MP, Fernández E, De Maeyer EAP, Verbeeck RMH, Boltong MG, Ginebra J, Driessens FCM, Planell JA. Setting reaction and hardening of an apatitic calcium phosphate cements. J Dent Res 1997; 76(4): 905-912.

  6. Fernández E, Gil FJ, Ginebra MP, Driessens FCM, Planell JA. Production and characterization of new calcium

  7. phosphate bone cements in the CaHPO4—a-Ca3(PO4)2 system: pH, workability and setting times. J Mater Sci Mater Med 1999; 10: 223-230.

  8. Ginebra MP, Driessens FCN, Planell JA. Effect of the size on the micro and nanostructural features of calcium phosphate cement: a kinetic analysis. Biomaterials 2004; 25: 3453-3462.

  9. Boltong MG, Fernández E. Common ion effect on some calcium phosphate cements. Clinical Materials 1994; 16: 99-103.

  10. Brown PW, Fulmer MT. The effects of electrolytes on the rates of hydroxyapatite formation at 25 and 38 °C. J Biomed Mater Res 1996; 31: 395-400.

  11. Ishikawa K, Ishikawa Y, Tagaki S, Chow LC. Properties and mechanism of fast-setting calcium phosphate cements. J Mater Sci Mater Med 1995; 6: 528-533.

  12. Li J, Liao H, Sjöström. Characterization of calcium phosphates precipitated from simulated body fluid of different buffering capacities. Biomaterials1997; 18: 743-747.

  13. Arai Y. Chemistry of powder production. Chapman & Hall, Great Britain, 1996.

  14. Ginebra MP. Desarrollo y caracterización de un cemento óseo basado en fosfato tricálcico-a para aplicaciones quirúrgicas. Tesis doctoral, Universitat Politecnica de Catalunya, Cataluña, España, 1996.

  15. Fernández E, Gil FJ, Best SM, Ginebra MP, Driessens FCM, Planell JA. Improvement of the mechanical properties of new calcium phosphate bone cements in the CaHPO4—a-Ca3(PO4)2 system: Compressive strength and microstructural development. J Biomed Mater Res 1998; 41: 560-567.

  16. Ginebra MP, Fernández E, Maeyer E et al. Setting reaction and hardening of an apatitic calcium phosphate cement. J Dent Res 1997; 76 (4): 905-912.

  17. Cullity BD. Elements of X-Ray diffraction. Addison-Wesley, USA, 1978.

  18. Jarcho M. Calcium phosphate ceramics as hard tissue prosthetics. Clinical Orthopaedics and Related Research 1981; 157: 259-278.

  19. Higgins TF, Dodds SD, Wolfe SW. A Biomechanical analysis of fixation of intra-articular distal radial fractures with calcium phosphate bone cement. J Bone and Joint Surg 2002; 84: 1579-1586.

  20. Bigi A, Panzavolta S, Rubini K. Setting mechanism of a biomimetic bone cement. Chem Mater 2004; 16(19): 3740-3745.

  21. Ginebra MP, Driessens FCM, Planell JA. Effect of the particle size on the micro and nanostructural features of a calcium phosphate cement: a kinetic analysis. Biomaterials 2004; 25: 3453-3462.

  22. Ginebra MP, Fernández E, De Maeyer EAP, Verbeeck RMH, Boltong MG, Ginebra J, Driessens FCM, Planell JA. Setting reaction and hardening of an apatitic calcium phosphate cements. J Dent Res 1997; 76(4): 905-912.

  23. Fernández E, Gil FJ, Ginebra MP, Driessens FCM, Planell JA. Production and characterization of new calcium phosphate bone cements in the CaHPO4—a-Ca3(PO4)2 system: pH, workability and setting times. J Mater Sci Mater Med 1999; 10: 223-230.

  24. Ginebra MP, Driessens FCN, Planell JA. Effect of the size on the micro and nanostructural features of calcium phosphate cement: a kinetic analysis. Biomaterials 2004; 25: 3453-3462.

  25. Boltong MG, Fernández E. Common ion effect on some calcium phosphate cements. Clinical Materials 1994; 16: 99-103.

  26. Brown PW, Fulmer MT. The effects of electrolytes on the rates of hydroxyapatite formation at 25 and 38 °C. J Biomed Mater Res 1996; 31: 395-400.

  27. Ishikawa K, Ishikawa Y, Tagaki S, Chow LC. Properties and mechanism of fast-setting calcium phosphate cements. J Mater Sci Mater Med 1995; 6: 528-533.

  28. Li J, Liao H, Sjöström. Characterization of calcium phosphates precipitated from simulated body fluid of different buffering capacities. Biomaterials1997; 18: 743-747.

  29. Arai Y. Chemistry of powder production. Chapman & Hall, Great Britain, 1996.

  30. Ginebra MP. Desarrollo y caracterización de un cemento óseo basado en fosfato tricálcico-a para aplicaciones quirúrgicas. Tesis doctoral, Universitat Politecnica de Catalunya, Cataluña, España, 1996.

  31. Fernández E, Gil FJ, Best SM, Ginebra MP, Driessens FCM, Planell JA. Improvement of the mechanical properties of new calcium phosphate bone cements in the CaHPO4—a-Ca3(PO4)2 system: Compressive strength and microstructural development. J Biomed Mater Res 1998; 41: 560-567.

  32. Ginebra MP, Fernández E, Maeyer E et al. Setting reaction and hardening of an apatitic calcium phosphate cement. J Dent Res 1997; 76 (4): 905-912.

  33. Cullity BD. Elements of X-Ray diffraction. Addison-Wesley, USA, 1978.




2020     |     www.medigraphic.com