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Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán

2004, Number 2

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Rev Biomed 2004; 15 (2)

Bacterial etiology and antibiotic susceptibility in patients with acne

Rodríguez-Cavallini E, Vargas-Dengo P

Language: Spanish
References: 22
Page: 101-106
PDF size: 35.18 Kb.


ABSTRACT

Introduction. The role of Propionibacterium acnes has been recognized in the development of acne. The most frequent bacteria isolated from acne lesions in patients from Costa Rica and their antimicrobial susceptibility pattern was determined in this work in order to contribute for better treatment orientation.
Material and methods. The lesions of 46 patients with acne vulgaris were studied for aerobic and anaerobic bacteria. Each isolate was identified using semi-automatized systems (API®) and the antibiotic susceptibility pattern was determined using the agar diffusion method or the disk dilution in broth, for aerobic and anaerobic bacteria respectively.
Results. 74% of the lesions showed mixed infections; Sthaphylococcus, as a single agent or combined with other agents, was isolated in 93% of the cases, Propionibacterium in 59 %, although only in 6.5 % of the cases as a single agent. Other agents found, although in a lower frequency, were Actinomyces, Peptostreptococcus, and Micrococcus. The antibiotic susceptibility pattern showed that 23% of Propionibacterium strains and 19% of Sthaphylococcus were resistant to clindamycin, 19% and 24 % to erythromycin, and 19 % y 39 % to tetracycline, respectively; three of the most frequently used antibiotics in the treatment of acne.
Discussion. This study confirms that not only Propionibacterium was involved in acne lesions. Although the treatment of acne is multifactorial, the knowledge of antimicrobial susceptibility of the principal agents has great importance, we hope that the data here shown can contribute to the knowledge of this pathology.


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