2009, Number 2
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Cir Cir 2009; 77 (2)
Comparison of 2-octyl cyanoacrylate adhesive and suturing for wound closure in the canine small bowel model
Escalante-Piña O, García-Nieto G, Hernández-Jasso AR, Reyes-Castellanos L, Flores-Aragón M, Rivera-Cruz JM
Language: Spanish
References: 19
Page: 121-125
PDF size: 144.37 Kb.
ABSTRACT
Objective: We undertook this study to evaluate 2- octyl cyanoacrylate glue and suture for wound closure in the small bowel.
Methods: This was a comparative and experimental study. Male and female domestic dogs (
n = 10) underwent a 2.0-cm small bowel closure of two wounds. All of these had closure with 2-octyl cyanoacrylate in the first wound. The controls (second wound in the same dog) were closed with suture. Four weeks later the wounds were observed to evaluate the repair.
Results: Wound closure time and macrophage count were lower with the 2-octyl cyanoacrylate glue than in the suture group.
Conclusions: 2-Octyl cyanoacrylate glue has the strength to seal a small bowel wound. The inflammatory response to the glue is lower than that of the suture at 4 weeks. These properties may make it a suitable material for replacing suture in a small bowel wound.
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