2005, Number 2
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Rev Mex Anest 2005; 28 (2)
Serum lactate in critically-ill patients in the postoperative period of abdominal surgery
de la Paz-Estrada C, Reyes-Rodríguez M, Barzaga-Hernández E
Language: Spanish
References: 21
Page: 69-73
PDF size: 60.10 Kb.
ABSTRACT
Objective: Evaluating the usefulness of lactate as a diagnostic test for complications in critically-ill patients undergoing abdominal surgery.
Material and methods: A prospective study was carried out in 198 patients randomly selected, admitted to Hospital «Guillermo Luis Fernández-Hernández Baquero”, Moa, Holguín, Cuba, from March, 2003, through February, 2004, to assess the usefulness of lactate values on admission for the diagnosis of intraabdominal septic complications in critically-ill patients undergoing abdominal surgery, and as a prognostic tool in these patients. Patients undergoing open abdominal surgical procedures at the first surgical stage were excluded from the study, as well as patients known to be diabetic and those in whom lactate was not measured on arrival. Participating patients were divided into two groups: Group I, with documented postoperative peritonitis, and Group II, with no postoperative peritonitis. In order to define the severity of disease in each study group, the APACHE II score was estimated on admission, and lactate levels were measured in a 2-ml sample of arterial blood.
Results: Significant differences in lactate levels were seen among patients who ultimately died and survivors (p ‹ 0.01). Septic intraabdominal complications occurred in 16.75%, whereas mortality was 31.81%.
Conclusions: Lactate measurements are a useful prognostic test in critically-ill patients undergoing abdominal surgery.
REFERENCES
Noris RG, Gordner LB. Trastornos ácido-básicos simples. Clin Med Norteam 1981;2:319-344.
Licea PM. Acidosis láctica: Diagnóstico y tratamiento. Rev Cub Med 1987;26(5):503-18.
Borde J. Value of blood lactate measurement for assessing acute ill patients III. In: James A. Kruse. Radiometer Medical. Copenhagen: Denmark, 1997:1-2.
McNelis J, Marini CP, Jurkiewicz A, Szomstein S, Simms HH, Ritter G, Nathan IM. Prolonged lactate clearance is associated with increased mortality in the surgical intensive care unit. Am J Surg 2001;182(5):481-5.
Shoemaker WC, Appel PL, Waxman K. Clinical trial of survivors cardiorespiratory patterns as therapeutic goals in critically ill post-operative patients. Crit Care Med 1982;10:898-903.
Mark PE, Varan J. The Hemodynamic derangement in sepsis. Implications for treatments strategies. CHEST 1998;114(3):854-60.
Sloden RN. Lactate in sepsis and trauma-hindrance or help? Anesthesical Intentioned Notfallmed Schmerzther 1999;34(4):237-38.
Reist K, Hilfiker O, Stepniewski MS, Heinzer I, Berchtold W, Reist U, Burgi U, Aeberhard P, Burgi W. Sepsis score in surgical intensive care medicine Anasthesiol Intensivmed Notfallmed Schmerzther 1998;31(9):556-62.
Eapen CE, Thomas K, Cherian AM, Jeyaseelan L, Mathai D, John G. Predictors of mortality in a medical intensive care unit. Natl Med J India 1997;10(6):270-2.
Bueno-Cavanillas A, Rodriguez-Contreras R, Lopez-Luque A, Delgado-Rodriguez M, Galves-Vargas R. Usefulness of severity indices in intensive care medicine as a predictor of nosocomial infection risk. Intensive Care Med 1999;17(6):336-9.
Hantke M, Holzer K, Thone S, Schmandra T, Hanisch E. The SOFA score in evaluating septic illnesses. Correlations with the MOD and APACHE II score. Chirurg 2000;71(10):1270-6.
Groeneveld AB, Hartenink KJ, de Gruat MC, Visses J, Thigs LG. Circulating endothelin and nitrate-nitrite relate to hemodynamics and metabolic variables in human septic shock. Shock 1999; 11(3):160-66.
Levraut J, Ciebiera JP, Chaye S, Rabary O, Jeanbau PCM, et al. Mild hypolactatemia in stable septic patients due to impaired lactate clearance rather than overproduction. Am J Resp Crit Care Med 1998;157(4):1021-26.
Henden HL. Peritonitis En: P Lawin. Cuidados intensivos. 2 ed. Española 1979;28(1):448.
Wahl W, Pelletier K, Schmidtmann S, Junginger T. Experiences with various scores in evaluating the prognosis of postoperative intensive care patients Chirurg 1996;67(7):710-7; discussion 718.
Marnitz U, Dauberschmidt R, Mrochen H. The value of blood lactate determination in the postoperative phase. Anaesthesiol Reanim 1994;19:103-9.
Linder MM, Krawczyk T, Lenz G. Significance of scores for therapy planning and evaluation of individual intensive care patients from the viewpoint of general surgery Langenbecks. Arch Chir Suppl Kongressbd 1998;113:299-302.
Bein T, Unertl K. Potentialities and limitations of the score system in intensive medicine Anasthesiol Intensivmed Notfallmed Schmerzther 1998;28:476-83.
Unertl K, Kottler BM. Prognostic scores in intensive care Anaesthesist 1997;46:471-80.
Foitzik T, Holle R, Schall R, Moesta T, Buhr HJ, Herfarth C. The Heidelberg Intensive Care Unit Score. Development of a computer-assisted scoring system for documentation of treatment course and assessment of prognosis in surgical intensive care patients. Chirurg 1995;66:513-8.
Kreuzer E, Kaab S, Pilz G, Werdan K. Early prediction of septic complications after cardiac surgery by APACHE II score. Eur J Cardiothorac Surg 1992;6:524-8; discussion 529.