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2008, Number 2

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Acta Pediatr Mex 2008; 29 (2)

Hepatic hamartoma associated with diaphragmatic hernia in a new born

Alvarado-León U, Palacios-Acosta JM, Chávez-Enríquez EP, Vázquez-Gutiérrez VM, Hernández-Carmona C

Language: Spanish
References: 15
Page: 109-113
PDF size: 504.47 Kb.


ABSTRACT

Mesenchymal hamartoma occurs in about 15 to 30% of all benign hepatic tumors usually in patients under 5 years of age. It is less common in neonates. Its origin is related to structural developmental alterations of the liver. Recent genetic studies have shown that translocation involving a common breakpoint in chromosomes 11 and 19 (q13-q13.4) may be involved. We present the case of a mesenchymal hamartoma of the liver in a one day old boy referred to our hospital. He presented with an extrathoraxic pediculated tumor on the right side; respiratory distress and absence of right radio and ulnar bones. The tumor was excised and a diaphragmatic hernia on the same side was repaired. A histological study indicated a mesenchymal hamartoma. The patient had a successful recovery. Mesenchymal hamartoma of the liver is a rare tumor usually of the right lobe of the liver. It presents with respiratory distress, an enlarged abdomen and a palpable mass. This patient had multiple bone malformations. Surgical resection, when possible, is the treatment of choice. Malignant transformation and recurrences are rare. Patients with mesenchymal hamartomas should be followed closely since spontaneous remissions are possible.


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