2008, Number 3
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An Med Asoc Med Hosp ABC 2008; 53 (3)
Subarachnoid anesthesia for cesarean section, effectiveness of ropivacaine with fentanyl at different doses for shorter latency
Ojeda VJF, Alamilla RC, Delgado CM, Castillo AR, Ruiz VR, Ramírez PA
Language: Spanish
References: 15
Page: 127-131
PDF size: 146.50 Kb.
ABSTRACT
Objective: To compare the effectiveness of ropivacaine ay different doses in spinal anesthesia for cesarean.
Methods: A prospective, random, double blind study. A selection of 60 women with full term pregnancy, ASA I and II, between 16 and 40 years of age, without analgesia in course, were assigned in two different groups (1) 10 mg, and (2) 12 mg ropivacaine plus 25 µg fentanyl respectively. The effective dose was that with a sensitive level in T4, of suitable density with duration for surgery and fewer collateral effects. Evaluation was for sensitivity, motor homodynamic behavior, maternal blockade, and adverse effects. Method was statistical, descriptive, Chi square, and exact Fisher.
Results: Demographic data did not show any statistical difference. Group 2 showed greater effectiveness regarding dose, and was considered statistically significant in relation to group 1, with a maximum metameric level (T4) (p ‹ 0.01), motor blockage for T1 with statistical difference (p ‹ 0.05). Maternal hypotension was more notable in group 2. Demographic and nutritional characteristics may account for the difference in our findings when compared to international literature.
Conclusions: 12 mg ropivacaine with 25 µg fentanyl applied in the subarachnoid cavity surpassed the effectiveness of 10 mg ropivacaine; although it appears to increase maternal hypotension thus requiring the use of ephedrine at dose-response. There were no repercussions in the mother-child binomial.
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