2005, Number 1
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An Med Asoc Med Hosp ABC 2005; 50 (1)
Nitric oxide versus milrinone in decreasing pulmonary hypertension crisis postventricular septal and atrioventricular septal defects surgery
Vázquez MJC, Archundia GA, Aceves CJL, Díaz QG, Laue NL
Language: Spanish
References: 17
Page: 15-18
PDF size: 51.75 Kb.
ABSTRACT
Background: Pulmonary hypertension crisis is the principal complication in patients with cardiac surgery for congenital cardiopathy.
Method: This is a comparative, observational and retrospective study of the experience in “Centro Médico Nacional 20 de Noviembre”, ISSSTE, with the use of nitric oxide and milrinone for the decrease of pulmonary hypertension crisis in surgical patients of ventricular septal and atrioventricular septal defects with pulmonary hypertension between May 2000 and October 2002. We included 30 patients, 15 treated with nitric oxide and 15 with milrinone. We analyzed age, sex, diagnosis, preoperatory and postoperatory pulmonary hypertension, intubation days, lenght of stay and days in the ICU, number of pulmonary hypertension crisis, treatment nitric oxide or milrinone and mortality.
Results: Both groups were similar except that the nitric oxide group had less pulmonary hypertension crisis, when compared with the milrinone group.
Conclusion: In our experience the nitric oxide was more effective than milrinone for the disminishment of pulmonary hypertension postoperatory crisis.
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