González-Arrieta ML, Martínez-Huerta MA, Ramírez-Ramírez ML

Language: Spanish
References: 19
Page: 19-25
PDF size: 178.51 Kb.

ABSTRACT

Determination of language dominance and motor areas is particularity important in preoperative evaluation of patient candidates for neurosurgical procedures because it can predict risk level of potential neurocognitive deficit postsurgery and develop functional maps that may be helpful in defining boundaries of surgical excisions. Objective: The objective of this study was to determine language dominance and motor areas using functional magnetic resonance imaging (MRI). This technique was validated by other authors using Wada test (3.6). In this case, we validated fMRI with Dichotic listering test. Material and methods: We performed fMRI in 10 right-handed subjects ranging in age from 20 to 72 years. fMRI was conducted on a 1.5-T GE Signa Highspeed employing BOLD echoplanar sequences in two different planes and an Advantage Windows Work Station (4.0). Language activation task was performed with block design and works generation on silent. Motor activation was performed with simple and complex uni- or bilateral movement. Determination of language dominance and motor areas is particularity important in preoperative evaluation of patient candidates for neurosurgical procedures because it can predict risk level of potential neurocognitive deficit postsurgery and develop functional maps that may be helpful in defining boundaries of surgical excisions. Objective: The objective of this study was to determine language dominance and motor areas using functional magnetic resonance imaging (MRI). This technique was validated by other authors using Wada test (3.6). In this case, we validated fMRI with Dichotic listering test. Material and methods: We performed fMRI in 10 right-handed subjects ranging in age from 20 to 72 years. fMRI was conducted on a 1.5-T GE Signa Highspeed employing BOLD echoplanar sequences in two different planes and an Advantage Windows Work Station (4.0). Language activation task was performed with block design and works generation on silent. Motor activation was performed with simple and complex uni- or bilateral movement. Results: Frontal areas involved in linguistic processing near Broca area were determinated in nine subjects in left hemisphere. Only one patient showed right hemispheric dominance. Conclusions: Application of fMRI in Neurosurgery is important and represents a unique tool that is safe, trustworthy, fast, and easy to use in patient candidates for this technique. We can use this technology in healthy subject for investigation goals.

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