2006, Number 2
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Rev Neurol Neurocir Psiquiat 2006; 39 (2)
A controlled study of negative symptoms in psychosis
Lara TH
Language: Spanish
References: 20
Page: 59-63
PDF size: 44.20 Kb.
ABSTRACT
Introduction. The concept of negative symptoms in schizophrenia is derived from Kraepelin’s description an reintroduced in 1974 by Strauss, Carpenter and Bartko and separated into three specific symptoms complexes: Positive symptoms (PS), negative symptoms (NS) and disorders of relating. Four symptoms have consistently loaded on the Negative symptom Factor: Affective flattening, Alogia, Avolition and Anhedonia.
Method. In this investigation we studied Positive and Negative symptoms through PANSS rating scale in three groups of 90 patients each: Paranoid schizophrenics, Non Paranoid Schizophrenics and Organic Psychosis included Schizophrenic like-psychosis.
Results. There are significant statistical differences between Schizophrenic and Non- Schizophrenic patients in Positive Symptoms and there are not significant differences in Negative symptoms.
Conclusions. There exist a strong relationship of NS with time of evolution, neuroleptic treatment with depot presentations and ECT, poor therapeutic adherence and poor environment in both groups.
REFERENCES
Buchanan RW. Negative symptoms: diagnosis, treatment and prognosis. Symposium Lundbeck de Esquizofrenia. Copenhague: Febrero 1996.
Buchanan RW, Carpenter WT. Domains of psychopathology: concept and validity. J Nerv Ment Dis 1994; 182: 193-204.
Buchanan RW, Brandes M, Breier A. Pharmacological strategies for treating negative symptoms. In: Breier A (ed.). The new pharmacotherapy of schizophrenia. Washington, DC: American Psychiatric Press; 1996.
Kane J, Honigfeld G, Singer J, Meltzer H, et al. Clozapine for the treatment-resistant schizophrenic: a double blind comparison with chloropromazine. Arch Gen Psychiat 1988; 45: 789-96.
Marder SR, Meibach RC. Risperidone in the treatment of schizophrenia. Am J Psychiat 1994; 151: 925-835.
Lara TH, Vélez BJA, De León A. Diagnóstico de la esquizofrenia. Un estudio crítico del programa piloto de esquizofrenia de la OMS. Psiquiatría.
Zamora LMA, Lara TH. Criterios diagnósticos de esquizofrénicos hospitalizados en el Servicio de Psiquiatría del INNN MVS. Arch Inst Nal Neurol Neurocir 1995; 10: 149.
von Knorring L, Lindstrom E. Principal components and further possibilities with the PANSS. Acta Psychiat Scand 1995; 388: 5-10.
Lindstrom E, Wieselgren IM, von Knorring L. Interreliability of the structured clinical interview for the Positive and Negative Syndrome Scale for schizophrenia. Acta Psychiat Scand 1995; 89(3): 192-5.
Peralta MV, Cuesta ZMJ. Validación de la escala de síntomas positivos y negativos (PANSS) en una muestra de pacientes esquizofrénicos. Actas Lusoesp Psiq Cienc Afines 1994; 22(4): 171-7.
Lara TH, Fernández ML, Reyes PN. Deterioro cognitivo en enfermos psiquiátricos crónicos. Memorias del VII Congreso Nacional de la APM. Morelia, Mich., 1985.
Nieto D. Cerebral lesions in schizophrenia. Its neuroanatomical and neurophysiological significance. Proc II Int Congress of Psychiatry, Zurich, 1957.
Nieto D. Bases cerebrales de la esquizofrenia. En: Nieto A (Ed.). La obra científica de Dionisio Nieto. México: UNAM; 1990, p. 129-39.
Aguirre VL, Coronado GN, Cortés BMC, Lara TH. La escala NOSIE en la evaluación de enfermos crónicos hospitalizados en el Servicio de Psiquiatría del INNN MVS. Memorias del XIV Congreso Nacional de la APM, Puerto Vallarta, Jal., 1995.
Cózatl RMA, Lara TH. Evaluación conductual de las técnicas de rehabilitación psicosocial en enfermos psiquiátricos y neurológicos hospitalizados en el INNN. XII Reunión Anual de Investigación del INNN. Mayo 23, 1997.
Lara-Tapia H, Montoya-Pulido, Zamora-Lira MA. An open trial of the antipsychotic effects of zuclopenthixol versus haloperidol in acute psychosis and exacerbation of chronic psychosis. Proc. X World Congress of Psychiatry. Madrid, Spain, 1996.
Díaz CP, Lara TH. Seguimiento telefónico y evaluación de la evolución de pacientes psiquiátricos problema después de su hospitalización. XII Reunión Anual de Investigación del INNN MVS. Mayo 23, 1997.
Córdova A, Duarte D, Rodríguez M, Puertas G. Rehabilitación de esquizofrénicos crónicos sometidos a un triple empuje: psicofármacos, psicoterapia de grupo y ergoterapia. En: Córdova CA (ed.). Teoría y práctica de la psiquiatría social. La Habana: Editorial Científico-Técnica; 1976.
Carpenter WT Jr, Heinrichs DW, Wagman AMI. Deficit and non deficit forms of schizophrenia: the concept. Am J Psychiat 1988; 145: 578-83.
Fenton WS, McGlashan TH. Testing systems for assessment of negative symptoms in schizophrenia. Arch Gen Psychiat 1992; 49: 179-84.