Álvarez CR, Antonio MM, Pérez VE, Chávez MÁ

Language: Spanish
References: 29
Page: 36-43
PDF size: 110.01 Kb.

ABSTRACT

Objective. To determinate laboratory values, choledochal diameter and relations between them which orientate to malignant pathology on ERCP. Background data. Foreign studies suggest malignity at older age, elevation of billirrubin, alkaline fosfatase, ALT and AST. We don’t have similar studies in our population. Methods. Patients for ERCP between September 2002 and October 2003 were selected at Hospital Juarez. Next values were documented: bilirrubin, ALT, AST, alkaline phosfatase (AP), DHL, lipase, amylase, hemoglobin, platelets, coagulation test, choledochal diameter, and histology test when indicated. Classified in two groups depending on benign or malignant pathology. We got correlation on each group using Pearson’s Coefficient and grope average for each variable. Results. We received 198 patients, 128 with benign and 45 with malignant pathology. Best correlation values were found between: AST and ALT, DB and IB, GGT and Lipase. At malignant group between: amylase and lipase, choledochal diameter and AP, AST and AP, ALT and AST, choledochal diameter and Hemoglobin. Larger differences of average between groups were found in decreasing order at: Lipase, Bilirrubin, GGT, Amylase, AP, AST and choledochal diameter. Conclusions. Our best suggestive of malignity were: elevations on: bilirrubin, GGT, AP, AST, dilated choledochal; diminution on lipase and amylase and a narrow proportion between lipase and amylase, AP and AST, choledochal dilatation and AP elevation or Hemoglobin diminution; and no narrow proportion between direct and indirect bilirubin.

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